Upstream bioprocessing is a fast-paced environment where thousands of samples are screened annually. The demand for sample analysis throughput and rapid method development is high. To meet throughput requirements and achieve a fast time to answer, well-established analytical technologies, such as conventional CE-SDS, SDS-PAGE, and LC/MS, may face challenges due to their traditionally low throughput and labor-intensive nature.

Discover solutions to address the analytical challenges in early drug development with streamlined workflows for protein purity analysis and fast glycan profiling. 

CE-SDS is the industry standard assay for assessing protein purity, integrity, and stability of biotherapeutics. Discover solutions to optimize this assay with validated kits and methods with the below content:

  • [Customer case study] Reduce the bottleneck in a process analytical sciences group at Johnson & Johnson Innovative Medicine. Discover how to incorporate new technologies into current process and accelerate cell line purity analysis
  • [Technical note] Learn how to convert single capillary workflows to higher throughput multi-capillary solutions
  • [Method optimization] Discover solutions to decrease turnaround time for the CE-SDS assay
  • [Technical note] Explore the advantages of parallel processing on the BioPhase 8800 system
  • [Technical note] Utilize the CE-SDS assay for development of AAV therapeutics

 

Glycan analysis provides key information on critical quality attributes that could affect stability, safety and efficacy of a protein therapeutic. Discover rapid solutions for N-glycan analysis in the content below:

  • [Customer case study] Explore a CE-based high-throughput method for monitoring the glycan profile of biologics
  • [Technical note] Enable glycan expression profiling of 96 samples in 90 minutes
  • [Technical note] Eliminate labor-intensive bench work and provide higher throughput N-linked glycan analysis with highly consistent results
  • [Technical webinar] Facilitate clone selection with high-throughput glycan profiling

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