DiscoveryQuant Software

DiscoveryQuant™ 3.0.1 Software

For research use only. Not for use in diagnostic procedures.

In drug discovery and development, sensitive, automated and rapid quantitative assays for drug-like molecules, which address the demands of fast-turn results in a high-throughput LC/MS drug candidate screening process, are increasingly prevalent.

DiscoveryQuant Software addresses these challenges in a comprehensive workflow. Compatible with all SCIEX Triple Quad, QTRAP, and TripleTOF systems, DiscoveryQuant Software reduces tedious LC/MS method development time with a fast, robust, and reliable process that optimizes methods for hundreds of small and/or large molecules.

Automated, efficient, rapid - for all types of molecules

Analyze and process multiple samples at the same time and expedite method development from existing database information

Access from anywhere with networked database and LIMS compatibility

Developed for all SCIEX MS platforms and seamlessly communicates with MultiQuant 3.0 Software

Status: Available

Streamlined Method Development for Bioanalytical Workflows

DiscoveryQuant™ Software significantly improves turn-around times in drug candidate analysis for high-throughput early ADME. It increases productivity by simplifying and expediting LC–MS method development cycle time for sensitive and selective bioanalytical assays, without compromising data integrity.

As a full-featured solution, DiscoveryQuant Software delivers fast, robust and reliable processing power for every aspect of the high-throughput quantitative workflow, from compound optimization to sample analysis.

Intuitive

Transition seamlessly from traditional small molecule method development to biotherapeutic assays, and leverage combined workflows that can optimize and analyze a variety of molecule types. You can also visualize all injections from your study on a single plot to improve trend analysis, and customize tables to suit different reporting formats.

Designed to ensure your success: DiscoveryQuant 3.0.1 Software offers rapid and automated optimization of multiple MRM conditions for your sensitive quantitative assay development needs. DiscoveryQuant supports method development and optimization for HT-ADME screening studies to select new drug candidates and offers high quality data with fast turnaround results for screening hundreds or thousands of compounds. This is all achieved with a single software program, comprising DiscoveryQuant Optimize and DiscoveryQuant Analyze.

Eliminate false positives: ChromaTune allows on-column MRM optimization to eliminate false positives with the ability to validate MRMs on column with QuickTune and FineTune. ChromaTune can screen compounds based on chromatographic properties, sensitivity, retention time, peak width and peak tailing, thereby offering a comprehensive compound summary panel for quick and easy review.

Succeed with small molecules and peptides: DiscoveryQuant supports HT-ADME screening for new biological entities and new chemical entities by improving the workflow for tuning and analysis of small peptides and large protein digests. Optimize fine tunes MRM conditions using real time labeling of y and b ions for even further confirmation. DiscoveryQuant also imports Skyline MRM transitions to its database for FineTune optimization.

Worry free integration: DiscoveryQuant 3.0 Software seamlessly integrates to MultiQuant 3.0.1 Software enabling enhanced batch processing for hundreds of samples with multiple MRM transition transitions to its database for FineTune optimization.

Intuitive interface and concise plate review: The graphical user interface of DiscoveryQuant Software has been designed to be intuitive and straight forward. It provides a full-featured solution to the discovery HT screening assay, plate-by-plate, compound-by-compound, and allows the drug discovery lab to meet its throughput objectives. DiscoveryQuant Software is built for speed, with quick review screens for clear optimization and assay results.

Time-saving templates: Choose your plate layouts from pre-defined templates so you can spend less time entering sample locations. Enter a few samples for a new plate and click "Propagate Groups" to auto-fill the rest based on the current, self-defined pattern. When you have plate after plate of samples to run, sample entry has never been easier, reducing the tedium typically associated with large-batch analysis.

Enterprise-wide solution: Use the global database support feature in DiscoveryQuant Software to store and share your mass spectrometry methods. Leverage the size of your organization to create greater sample capacity and productivity by drastically reducing redundant work. The software will automatically look for an existing method in the database before acquiring data to build a new one. Communicate with your preferred LIMS and also with your compound library to store data and share across the enterprise.

Save time: DiscoveryQuant Software has been conceived by experts in early-ADME drug discovery who understand the intricacies of this application. This software has been carefully designed to deliver high-throughput analysis, without compromising on the quality of the results; you will no longer sacrifice one for the other. Use a visual approach; create templates that can be used for frequently run studies, which include sample assignment, quantitative information and internal standard assignment.

Easy review, data analysis, and report generation: All injections from a study can be visualized on a single plot to improve trend analysis, and customizable tables allow tailoring of DiscoveryQuant Analyze to suit customer report formats.

RUO-MKT-18-2013-A

Title	Date
DiscoveryQuant Software Masterclass Series -Video 4	03/11/2019
DiscoveryQuant Software Masterclass Series - Video 1	03/11/2019
Introducing DiscoveryQuant Software	08/14/2018
SCIEX Quantitation and Metabolism Solutions Brochure	05/26/2017
DiscoveryQuant 3.0.1 Release Notes	12/10/2015
DiscoveryQuant Product Bulletin	12/10/2015
Signature Peptide MRM Optimization Made Easy for Therapeutic Protein and Peptide Quantification	12/01/2015
DiscoveryQuant 3 Software Overview	10/27/2014
Better, Faster, Easier: software for method development of new chemical and biologic enities	09/23/2014

Title

Date

DiscoveryQuant Software Masterclass Series -Video 4

03/11/2019

DiscoveryQuant Software Masterclass Series - Video 1

03/11/2019

Introducing DiscoveryQuant Software

08/14/2018

SCIEX Quantitation and Metabolism Solutions Brochure

05/26/2017

DiscoveryQuant 3.0.1 Release Notes

12/10/2015