Analyst TF (TripleTOF systems): ITC for MS/MS based on precursor intensity


In Analyst TF, the ITC in MS/MS mode currently regulates the ion beam based on the ion densitiy in the TOF-MS scan. It would make more sense to regulate it based on the intensity of the precursor, similar to what we do in Sciex OS for the X500R. This would help a lot in terms of linearity in MS/MS, e.g. for quantification of multiply charged peptides for which the linearity of the detector is reduced.


0 Comments Jun 18, 2019 4 Views Product: Analyst TF Software