Signal enhancement maximized through intelligent chemistry
For research use only. Not for use in diagnostic procedures.
Amplifex Keto Reagent is designed specifically to enhance signal strength up to 500-fold (depending on the analyte).
The Amplifex Keto Reagent is a universal reagent that reacts with a molecule's keto or aldehyde functional group, such as the ketone in ketosteroids (e.g., testosterone).
With the Amplifex Keto Reagent, your sample size can be dramatically reduced, while still achieving LLOD and LLOQ levels that were difficult, if not impossible, by mass spectrometry analysis even on the most-sensitive platforms.
- Intelligent design boosts ionization efficiency and improves fragmentation
- Substantial reduction in sample volume and analysis time is enabled.
- Reactions are simple (one-step derivatization) and fast (30-60 minutes).
- Universal derivatization technique reacts with all molecules containing the keto or aldehyde functional groups
Status: Available 
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Designed specifically to enhance sensitivity of trace analytes and enable workflows that push the limits of sample volume
Amplifex Keto is a customized derivatizing reagent designed to react specifically with a molecule's keto and aldehyde functional groups to improve ionization efficiency. (i.e. Amplifex™ Keto Reagent treatment results in a sensitivity enhancement of ~40-fold in testosterone and universally reacts with all ketosteroids across an array of sources (plasma, dried blood spot, dialyzed samples, urine, and oral fluids).
Signal enhancement for testosterone
Amplifex Keto Reagent is designed to boost signal intensity for all ketosteroids. Here is an example of a 40-fold increase in sensitivity for testosterone.
Signal enhancement for molecules with keto or aldehyde funct
Amplifex Keto Reagent is intelligently designed to derivatize any molecule's keto or aldehyde functional groups. See examples of additional compounds.
Derivatizes across an array of matrices
Amplifex Keto Reagent is not limited to one sample matrix. The reagent will derivatize molecules in dried blood spots, plasma, dialyzed samples, urine, and oral fluids.
Derivatizes across an array of matrices
Amplifex Keto Reagent is not limited to one sample matrix. The reagent will derivatize molecules with dried blood spots, plasma, dialyzed samples, urine, and oral fluids.
Amplifex Keto Reagent workflow
The Amplifex Keto Reagent derivatization and sample preparation workflows are quick (30 minutes), simple (one-step), reproducible, robust, and high-yielding regardless of sample matrix.
Kits |
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Part Number | Kit Name/ Description |
4465962 | Amplifex Keto Reagent Kit |
4466055 | Amplifex Keto Prep Starter Kit |
4466054 | Amplifex Keto Cartridge Kit |
4466179 | Amplifex Keto Plate Kit |
5028174 | Amplifex Prep Replacement Solvent Guide |