The SCIEX discovery metabolomics workflow can uncover and identify new compounds that could be putative biomarkers or key elements of important metabolic pathways. With the power of the TripleTOF® system, there's no need to choose between data acquisition methods. With one sample injection, you can process your data to screen for unknown metabolites or focus on only those compounds of interest with a targeted metabolite screening approach.
Unknown Metabolite Screening: When little information exists about a sample, or new information is desired, this data processing approach will allow you to discover all compounds that are different between samples. With XCMSplus software you can simultaneously quantify and identify thousands of features across hundreds of samples and search the METLIN database to identify metabolites of interest.
Targeted Metabolite Screening: When you want to extract information for known compounds, this data processing approach enables hypothesis-driven data analysis. Using MasterView™ software, and the Accurate Mass Metabolite Spectral Library you can concentrate on finding and quantifying changes between known compounds, such as all metabolites within a specific biochemical pathway. Then MultiQuant™ software and MarkerView™ software enables rigorous quantitation and statistical analysis of those compounds across hundreds of samples.