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Entre en una nueva era de sensibilidad e innovación en LC-MS/MS con el sistema de LC-MS/MS SCIEX Triple Quad™ 7500 - QTRAP® Ready. Llegue más lejos superando los límites de sensibilidad, los objetivos de productividad, y los desafíos de fiabilidad y potencia actuales. Sea el primero en lograr nuevos descubrimientos con esta innovación.
Experimente extraordinarias mejoras de sensibilidad con el sistema SCIEX 7500. Comience a detectar lo que antes era indetectable y cuantifique a niveles más bajos con una precisión impresionante.
Amplíe las capacidades de su laboratorio para analizar muestras sucias y complejas. La nueva guía de iones D Jet™ le permitirá caracterizar analitos que antes quedaban enmascarados por matrices.
Cuantifique más trazas de analitos en niveles inferiores. Simplifique la preparación de muestras e inyecte menos muestras con la fuente de iones OptiFlow® Pro. Además, podrá aumentar la transición de iones cruciales al sistema con la tecnología E Lens™ integrada.
El sistema SCIEX 7500 ofrece el mayor nivel de sensibilidad de todos los sistemas SCIEX. Se han logrado importantes avances en el análisis de analitos clave que requieren límites de cuantificación más bajos. La innovación de este producto permite la cuantificación de bajos niveles de muestras crudas y complejas para impulsar su investigación. Además, puede ampliar y simplificar su flujo de trabajo con un rango dinámico lineal de hasta seis órdenes de magnitud.
La fuente de iones Turbo V™ ha evolucionado. La fuente de iones OptiFlow Pro incorporada en el sistema SCIEX 7500 permite detectar analitos en muestras crudas o complejas. La fuente OptiFlow Pro incorpora la tecnología E Lens, que mejora la transferencia de iones al espectrómetro de masas. La modularidad de la fuente OptiFlow Pro permite cambiar fácilmente de flujo alto a flujo bajo y entre ESI y APCI, rápidamente. Aumente la sensibilidad de su estudio con el sistema SCIEX 7500 para obtener un perfil más exacto de la muestra. El mayor tamaño del orificio permite la entrada de una cantidad mayor de iones en el espectrómetro de masas y el diseño exclusivo de la guía de iones D Jet retiene y captura más iones a través de la pluma de pulverización de ESI.
Traslade su flujo de trabajo a este instrumento altamente sensible y compruebe rápidamente mejoras significativas en términos de productividad. Este diseño renovado le permitirá probar más muestras y detectar compuestos de traza imposibles de ver anteriormente en ningún otro sistema SCIEX. El sistema SCIEX 7500 utiliza el software SCIEX OS, una plataforma para esta próxima generación de espectrómetros de masas. Las funciones y características tradicionales del software se complementan con ayudas visuales y componentes que permiten revisar los datos con rapidez, precisión y fiabilidad.
Analice y represente sus datos en un formato nuevo e intuitivo. Controle, adquiera, analice, examine e informe, todo en una única plataforma de software.
Nuevos niveles de cuantificación
Gracias al sistema SCIEX 7500 con el software SCIEX OS incorporado
With a simple upgrade path this system can offer additional QTRAP functionality scan types. Pairing conventional MRM workflows and Enhanced Product Ion scans can enable improved confidence in acquired data. MRM3 workflows can push quantification levels through matrix interferences.
Get a stronger gradient around the orifice and protect your precious and limited sample. With the E Lens Technology, the power and efficiency of the SCIEX Turbo V Ion Source geometry is enhanced in the new OptiFlow Pro Source, which focuses transmission of the ESI plume into the orifice of the system.
Execute fast interchanges between high flow and low flow to adapt to your workflow needs. The OptiFlow Pro Source introduces a new modularity feature and incorporates the reliability and efficiency of the legendary Turbo V Ion Source.
Capture more of the ESI plume and retain more of the important ions than with previous technologies. The D Jet Ion Guide concentrates the samples and removes the gas molecules and neutral ions.
Attain lower levels of quantification compared to other SCIEX instruments. The precise and robust engineering of the ion rail allows consistent and reproducible analysis time after time, by focusing the crucial ions that you need for your workflow.
SHANE NEEDHAM
Director científico fundador
Alturas Analytics, Moscow, Idaho
BERNARD BAJEMA
Jefe de proyecto
Vitens, Países Bajos
WIM BROER
Director, Ciencia y desarrollo
Nofalab, Países Bajos
RONNY BOSCH
Analista sénior
Vitens, Países Bajos
El rápido avance del proceso de desarrollo de fármacos exige sensibilidad para permitir una caracterización farmacocinética más completa de los candidatos a fármacos de dosis bajas, por debajo de los límites de detección. El sistema SCIEX 7500 permitirá a los investigadores farmacéuticos seguir analizando dosis inferiores, compuestos de mayor eficacia, así como mejorar la eficiencia del bioanálisis rutinario.
VER NOTAS TÉCNICASIn drug discovery, being able to make pharmacologically relevant measurements of drug candidates and evaluate the transporter at early-stage development is crucial when selecting drug safety profiles. The 7500 System offers you enhanced sensitivity to reduce compound concentrations, so it’s more biologically relevant. Download the technical note to see how you can get higher-quality data.
VER NOTAS TÉCNICASQuantification of peptide/protein therapeutics in biological matrices is crucial for therapeutic development. Download the technical note that demonstrates a robust method using the SCIEX 7500 System to quantify a series of surrogate peptides in rat plasma at ultra-low LLOQs —5 to 39 fmol/mL.
VER NOTAS TÉCNICASQuantifying intact peptide hormone analogs is challenging for because of low ionization and CID fragmentation efficiency related to the high molecular weights, low concentrations in matrices that require ultra-high assay sensitivity, and endogenous inferences from natural intact peptide hormones. Enter the SCIEX 7500 System. Read more about the sensitive LC-MRM method to quantify intact peptide hormones in rat plasma.
VER NOTAS TÉCNICASQuantifying trace level cyclic peptides in biological matrices is extremely challenging. The SCIEX 7500 System can offer outstanding reproducibility, precision, accuracy, and linearity to ease these challenges. Download this ultra-sensitive MRM based cyclic peptide quantification workflow.
VER NOTAS TÉCNICASThere are important requirements for the quantitative measurement of host cell proteins (HCP) across the entire development paradigm. Learn about the targeted high sensitivity, analysis throughput, robustness and multiplexing capability approach using the SCIEX 7500 System.
VER NOTAS TÉCNICASThe complexity of the lipidome is very high with a huge diversity in lipid molecular species making comprehensive quantitative profiling challenging. Download this technical note to find out about a targeted MRM assay approach which enables quantification of a broad array of different lipids at the molecular species level using the SCIEX 7500 System.
VER NOTAS TÉCNICASQuantitative robustness remains key, to ensure both large and small biological changes are accurately measured across large sample cohorts. The SCIEX 7500 System offers you high sensitivity as well as wide linear dynamic range for large scale targeted peptide quantification.
VER NOTAS TÉCNICASDetecting and quantifying pesticide residues in food remains a moving target as food regulations drive the pursuit of lower limits of quantification. This work demonstrates the high sensitivity of the SCIEX 7500 System in quantifying 209 pesticides, easily achieving sub-ppb detection limits with a very small injection volume.
VER NOTAS TÉCNICASThe global scale of pesticide use, its impact on food safety and authenticity regulations have led to the need for sensitivity analysis that can achieve trace levels. Download the technical note to learn more about how the SCIEX 7500 System offers sensitivity, robustness and accuracy with 700 compounds achieving limits low as 0.2 ng/mL.
VER NOTAS TÉCNICASDrinking water analysis is subjected to extremely low and rigid prescribed consent values (PCV) for determinands, including pesticides, pharmaceuticals and personal care products. In collaboration with Vitens Water Company, we demonstrated the sensitivity levels of the SCIEX 7500 System for low-level quantification across a relatively large suite of 431 determinands.
VER NOTAS TÉCNICASAs the cannabis market emerges globally, more stringent and lower level pesticide regulations may come into force. The SCIEX 7500 System shows its levels of sensitivity across a broad suite of regulated pesticides coupled with ruggedness and robustness for continued analysis of cannabis extracts.
VER NOTAS TÉCNICASIn a forensic laboratory, the ability to accurately quantify large panels of analytes in complex biological matrices over a wide range of concentration is challenging and often requires dilution of the samples to bring them within the calibration range of the instrument. In this technical note, the SCIEX 7500 System demonstrates exceptional performance in speed, linear dynamic range and sensitivity to overcome this challenge, quantifying a panel of 49 drugs in human whole blood.
VER NOTAS TÉCNICASSí, deseo obtener más información sobre el sistema de LC-MS/MS SCIEX Triple Quad 7500 - QTRAP Ready.
The SCIEX clinical diagnostic portfolio is For In Vitro Diagnostic Use. Rx Only. Product(s) not available in all countries. For information on availability, please contact your local sales representative or refer to https://sciex.com/diagnostics. All other products are For Research Use Only. Not for use in Diagnostic Procedures. Trademarks and/or registered trademarks mentioned herein, including associated logos, are the property of AB Sciex Pte. Ltd. or their respective owners in the United States and/or certain other countries. The images shown may be for illustration purposes only and may not be an exact representation of the product and/or the technology. Echo and Echo MS are trademarks or registered trademarks of Labcyte Inc. in the United States and other countries, being used under license by SCIEX. Plates are available from Beckman Coulter Life Sciences. AB Sciex™ is being used under license. RUO-MKT-18-11611-A