32 Karat software fails to open correctly and displays an "Unable to create a required Enterprise folder" error message

For research use only. Not for use in diagnostic procedures.

Issue Description

After Windows updates are installed, 32 Karat software fails to open correctly and displays an "Unable to create a required Enterprise folder" error message.

Possible causes:

The error is generated by “CSMainApp::UpgradeEnterpriseFolder” when the program attempts to access the incorrect directory path where the Enterprise SW is installed, which is stored in the registry, "HKEY_LOCAL_MACHINE\SOFTWARE\WOW6432Node\ChromatographySystem\C:/32Karat" with value "ChromDir", which should be "C:\32Karat".

Resolution

The folder “C:/32Karat”, which is referred to as the registry key, must be edited.

1. Reboot the system to ensure that the 32 Karat software and other background processes are not running.

2. Click the magnifying glass icon on the Windows taskbar, then entering “regedeit” in the Windows search bar to locate the Registry Editor.

3. Open the Registry Editor, navigate to Computer\HKEY_CURRENT_USER\SOFTWARE\Classes\VirtualStore\MACHINE\SOFTWARE\WOW6432Node\ChromatographySystem and delete the C:/32Karat key.

4. Navigate to Computer\HKEY_LOCAL_MACHINE\SOFTWARE\WOW6432Node\ChromatographySystem\C:/32Karat

5. Select the C:/32Karat folder, right-click and select Export. Save the registry file.

6. In Windows File Explorer, select the exported registry file, right-click and select Edit in Notepad.

7. Select Edit and select Replace. 

8. In the Find what field, enter HKEY_LOCAL_MACHINE. In the Replace with field, enter HKEY_CURRENT_USER\SOFTWARE\Classes\VirtualStore\MACHINE.

9.   Click “Replace All”.

10. Select File and select Save.

11. Double-click on the registry file to import into the registry. This procedure will work the first time that this error occurs, but you may need to update the registry key at a later date if the same error message is displayed. 

Procedure if the error happens at a later date after initial registry key updates

1. Navigate to Computer\HKEY_CURRENT_USER\SOFTWARE\Classes\VirtualStore\MACHINE\SOFTWARE\WOW6432Node\ChromatographySystem\C:\32Karat and export the registry key.

2. Double-click on the registry file to import into the registry.