How to modify ParameterSettings for APCI “Compound Optimization” in Analyst® software?

For research use only. Not for use in diagnostic procedures.

Answer

The settings for "Compound Optimization" are optimized for ESI and low flows. If "Compound Optimization" with the APCI probe and a flow of at least 200 µl/min is used more often, save the settings for low and higher flows separately.

The settings are found in the following Windows folder:
Analyst Data > Projects > API Instruments > Parameter Settings

The file is called:


Save this file as a backup in case you change parameters and do not longer know what they were before.
Analyst® software requires that the file is called ParamSettingsDef.psf. Change the name of the file accordingly when switching between APCI / ESI or low / high flow.

The Parameter Settings in Analyst® software are located here:



At the top find the name ParamSettingsDef.psf.
Select the "Scan Category". For positive "Q1 + Scan and MS/MS + Scan" and negative correspondingly "Q1 - Scan and MS/MS - Scan".
Adjust depending on the flow rate and the device type:
GS1, GS2, CUR, TEM