What Integration Algorithms Are Used by SCIEX OS Software?

For research use only. Not for use in diagnostic procedures.

Answer

The SCIEX OS software has three integration algorithms that can be used to integrate peaks, and these options are listed in the Project Default Settings in the Analytics module:

1. MQ4 - Selects a low concentration, but not the lowest concentration, standard or quality control sample by default as the representative sample of the analytical run.
2. AutoPeak - Selects a high concentration, but not saturated, standard or quality control sample by default as the representative sample of the analytical run.
3. Summation - Does not perform a normal peak search, but assumes that a peak is present close to the expected retention time.

It is also possible to manually integrate peaks that were missed by the algorithms. 

For additional details on integration algorithm parameters, please see the Sciex OS Software User Guide, page 169.