Why SCIEX OS does not create a .wiff file with certain configuration of acquisition mode ?

For research use only. Not for use in diagnostic procedures.

Answer

Here is the list of conditions for which there is no creation of a wiff file, with only a wiff 2 for SCIEX OS.

The following exceptions apply:

Nominal Mass: 

• Overlapping scheduled experiment (e.g. experiment 1 = 0 to 2 min, experiment 2 = 1 to 2 min, where the two experiments are overlapping from 1 to 2 min)
• Looped IDA (e.g. MRM+ IDA, IDA + IDA) 
• 3 or more MRM experiments (e.g. MRM + MRM + MRM) 

• Scheduled experiment (both overlapping and/or non-overlapping)
• Q1 
• Combinations of IDA + (s)MRMHR
• Combinations of (s)MRMHR + IDA
• Combinations of IDA + IDA
• Combinations of IDA + SWATH
• Combinations of SWATH +IDA
• Combinations of SWATH +(s)MRMHR
• Combinations of (s)MRMHR +SWATH