Intabio ZT system
Comprehensive charge variant analysis made simple
The Intabio ZT system couples icIEF separation and UV detection
with high-resolution mass spectrometry for peak identification.
System benefits:
Comprehensive proteoform identification in minutes
The process of identifying individual charge variant components and interpreting their structural differences conventionally takes weeks and requires the use of multiple instruments, with multiple manual steps.
With the Intabio ZT system - separation, quantitation and identification of individual charge variants can be achieved in minutes on a single platform.
Technology:
Leverage key analytical functions with microfluidic chip-based technology
The Intabio ZT cartridge enables key analytical functions using proprietary microfluidic chip-based integrated icIEF-UV/MS technology.
- Separation of charge variants with imaged capillary isoelectric focusing (icIEF)
- Quantitation with real-time UV detection
- Electrospray ionization for further mass spectrometry identification
Wherever you play in the pipeline, change the game in modern medicine
Clone selection, cell line development
Intact protein analysis, charge variant analysis, PTM characterization
Process development
Charge variants, glycoforms, PQA assessment
Formulation
Stability/degradation
Manufacturing attribute monitoring
CQA and PQA monitoring
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Associated applications
Charge variant analysis
Achieve the full picture and accelerate decisions with comprehensive characterization of biopharmaceutical charge variants.
Intact protein analysis
Confidently select lead candidates and ensure reproducible product quality. Fast and reliable protein analysis solutions that simplify identification and characterization of complex molecules at the intact level.