The Power of Precision
ZenoTOF 7600 system
SCIEX 7500 system
SCIEX Triple Quad 6500+ system
SCIEX 5500+ system
QTRAP 6500+ system
QTRAP 4500 system
View all mass
Intabio ZT system
Echo MS system
2.0 High Throughput Multiplexing system
View all integrated
BioPhase 8800 system
8000 Plus system
800 Plus system
Advance your research with front-end
instruments designed to help you realize the full power of your mass
spectrometer. SCIEX has the broadest portfolio of ESI-MS front-ends
can facilitate various flow rates, sample requirements and
sensitivities. No one else offers the entire range
flow, microflow, nanoflow LC-MS and even ultra-low flow
ExionLC 2.0 series
View all front-end HPLC MS
Differential mobility spectrometry (DMS) and
ion mobility spectrometry are analytical techniques used to separate
ions based on their gas phase mobility. Multiple types of ion
devices exist, such as drift tubes, traveling wave, and high-field
asymmetric waveform devices. Learn how you can separate yourself
Differential Ion Mobility.
The latest ion sources from SCIEX enable
enhanced sensitivity and robustness with greater desolvation range
across all MS platforms, from Triple Quad to QTRAP and QTOF.
Turbo V ion
OptiFlow Turbo V ion
View all ion sources
vMethod applications are pre-configured and verified LC-MS/MS
that reduce the need for method development – significantly cutting
time, effort and money to deploy a new assay. Every vMethod provides
method conditions, recommended sample prep, LC and MS conditions,
details for applicable MS/MS library databases for key applications.
and personal care products (PPCPs)
and protein bioanalysis
Explore vMethod applications
feature request portal
Analyst TF software
Biologics Explorer software
Molecule Profiler software
High resolution and QTRAP
libraries can dramatically enhance the quality of your analysis,
you much improved confidence in your data. With a comprehensive
at your fingertips, you can easily create methods and process
and non-targeted screening data on your complex samples, faster and
easier than ever before.
All in one
HR-MS/MS library with NIST 2017
Explore the library
Boost the performance of your mass
spectrometer and improve sensitivity, productivity, and data
iChemistry Solutions are the world's only reagents and
that are custom designed with your success in mind.
RNA 9000 Purity & Integrity kit
kit for amino acid analysis of hydrolysates
kit for amino acid analysis of physiological fluids
protein digestion solution
Protein CE-SDS Purity Analysis kit
MS calibration kits
CZE rapid charge variant analysis kit
BioPhase Fast Glycan Labeling and Analysis kit
standards kit for pesticide analysis
auEChERS extraction and dispersive kit
Ampliflex keto reagent
View all consumables
QTOF – Quadrupole
Time of Flight
QTRAP® – Triple Quad Linear
SWATH® – Data Independent
SelexION® – Differential
MicroLC – Microflow
View All Technology
ADME and DMPK
Viral vector characterization
High-throughput mass spectrometry
Targeted protein degraders and PROTACs
Extractables and leachables
Residual nucleic acid analysis
Lipid nanoparticles and non-viral carrier
Messenger RNA analysis
Plasmid and DNA analysis
Synthetic oligonucleotide analysis
Cell line analysis
Charge heterogeneity analysis
Intact protein analysis
Peptide mapping analysis
Subunit mass analysis and middle-down
View all Biopharma and pharma
Clinical Mass Spec Operators
Clinical Method Developers
Clinical Lab Managers
View All Clinical
Pesticides & herbicides
Soil and biota
View All Environmental
How do you protect your reputation and meet today’s global food
standards? Whether you are a commercial lab or a food manufacturer,
quality of your food testing data is vital to your business. SCIEX
solutions help you meet maximum residue limits (MRLs) with
data that you can genuinely count upon. With a portfolio of
applications, your lab can quickly and easily react to diverse
Authenticity & Profiling Analysis
& Food Contact Substance Analysis
Food and Beverage Testing
How do you ensure the integrity of your
results in an industry that is never constant? By accurately
even the smallest compound angles you can deliver evidence that
SCIEX forensic analysis solutions deliver fast, highly accurate
data across a multitude of compounds and biomarkers, from the known
the new and novel.
Homeland security (coming soon!)
Cannabis and hemp potency testing
Doping control (coming soon!)
View All Forensic
Metabolic Flux Analysis
and SNP Analysis
View All Life
The SCIEX Now Learning Hub offers the most diverse and flexible learning options available, with best-inclass content that helps you to get the most out of your instrument and take your lab to the next level. Available personalized learning paths based on the latest memory science ensure better knowledge retention, and automated onboarding and enrollment means you’ll get up and running faster.
SCIEX Now Learning Hub offers the most diverse and
flexible learning options available, with best-in-class content that
helps you to get the most out of your instrument and take your lab
the next level. Available personalized learning paths based on the
latest memory science ensure better knowledge retention, and
onboarding and enrollment means you’ll get up and running faster.
SCIEX Learning Manager provides you with the infrastructure to assign, monitor and report on your staff's
competency through a single digital platform. Effectively manage the training process for new hires, ensure
continuous staff development and access information with a single log-in to your SCIEX account.
You can browse, filter, or search our
extensive list of training offerings. Choose from over 100
eLearnings or search for an instructor-led course near you. Once you
select the course you want to take, you will be directed to
Learning Hub for enrollment (login required).
Login to SCIEX Now Learning Hub
Success Programs at Your
Scientist Training at Your Site
Visit all Training
SCIEX Now Learning Hub
Manage my instruments
SCIEX Now New Feature Request
Visit your SCIEX
Declaration of conformance
Safety data sheets
Certificates of analysis
View All regulatory documents
Software and IT services
LC-MS service plans
Protect Plus Suite for your new LC-MS
CE service plans
Clinical service plans
StatusScope remote monitoring
Software accelerator program
Software support plans
Software support policy
Premium access content
Academic partnership program
View all partnership programs
Join the SCIEX community today to
interact with your peers, share and exchange ideas, develop
your knowledge, stay up-to-date with the latest products,
post insights and questions, comment on others and receive
support. This community is designed to help you, our
customers, move science forward and get the answers you
need. We’re committed to engaging with and listening to you,
to create the best customer experience possible and to
contribute to the success of your work.
Environmental / Industrial
Food and Beverage
Life Science Research
Now Feature Requests
View All Community
Echo® MS Center Of Excellence
Our favorite papers
Meet our executives
In the news
You've got questions. We've got experts who
can help. Contact us to find out more, talk to a specialist, explore
solutions or get expert support.
Request a quote
SCIEX success network
Request hosted catalog
Global public relations
Bosnia and Herzegovina
United Arab Emirates
United Republic of Tanzania
AB Sciex is doing business as SCIEX. © 2010-2018 AB Sciex. The trademarks mentioned herein are the property
of the AB Sciex Pte. Ltd. or their respective owners. AB SCIEX™ is being used under license. Beckman
Coulter® is being used under license. Product(s) may not be available in all countries. For
information on availability, please contact your local representative. For
research use only. Not for use in diagnostic procedures.
SCIEX and IROA Technologies LLC to Offer Complete Solution for Next Generation Metabolomics, to Allow Unambiguous Identification and Quantitation of Metabolites in a sample
Framingham, MA — SCIEX, a global leader in life science analytical technologies, today announced a co-marketing agreement with IROA Technologies LLC, a reagents and kits company specializing in metabolomics analyses. This relationship will uniquely position SCIEX to address a major challenge in untargeted metabolomics analyses, namely metabolite identification, by enabling and automating the measurement of biochemicals in biological systems.
Under this Agreement, IROA Technologies and SCIEX will promote a unique labeling kit called the IROA Workflow Kit with SWATH® Acquisition based on next-generation metabolomics and TripleTOF® Systems. This focus on improving metabolite identification while improving quantitative accuracy will enable scientists to differentiate the real biochemical signatures from the noise allowing higher confidence in their analyses of complex sample types, potentially yielding superior biological insights and discoveries.
IROA® is an isotopic methodology in which all biological molecules are uniformly and randomly labelled to create informative isotopic patterns that are readily discriminated from artifacts. Because of the uniform nature of the labelling, these patterns show up in not only the MS, but also in all fragments in any subsequent MS/MS.
Isotopic Ratio Outlier Analysis IROA is a simple and direct metabolic profiling technique in which specific and unique signatures or (tags) are embedded into biochemical metabolites for relative quantitation by mass spectrometry (MS) and uses software algorithms to find, identify and quantitate these specific signatures.
"The combination of SWATH and IROA improves global metabolomic workflows by enabling reference to a 13C isotopic standard, enhancing the identification of both known and unknown metabolites, and will ultimately improve quantitative performance of hundreds of metabolites in a single injection," states Dr. Tim Garrett, Associate Professor at University Florida School of Medicine.
SWATH Acquisition, a data independent acquisition (DIA) workflow is well adopted in quantitative discovery proteomics, and is now starting to take off in untargeted metabolomics workflows. SWATH allows a user to collect MS and MSMS of every detectable peak in their sample, thus creating a digital map of the metabolome. Variable Window SWATH (an enhanced way of collecting MSMS, using narrower mass windows in denser regions of the MS spectrum) allows for specificity. The major advantage is that there is a huge enhancement of data quality through data reduction by removal of background/noise and keeping only the biologically relevant peaks, thereby eliminating false discovery.
"Advancing precision medicine by reproducibly quantifying hundreds of metabolites in large sample cohorts is of high importance to both academic and clinical research labs," said Mark Cafazzo, Director of Strategic Market Management at SCIEX. "The use of IROA with variable window SWATH Acquisition allows researchers to collect comprehensive data from complex mixtures for identification and quantitation in a single injection, and then rapidly reduce the complexity of the results, accelerating the identification of biologically-relevant metabolites. By partnering with IROA Technologies and adding the IROA Workflow Kit to SCIEX next-generation metabolomics solutions, we help scientists address the metabolite identification challenges they face every day, especially when working with complex samples."
Learn more about SCIEX Metabolomics Solutions and IROA Technologies Products.
SCIEX helps to improve the world we live in by enabling scientists and laboratory analysts to find answers to the complex analytical challenges they face. The company's global leadership and world-class service and support in the capillary electrophoresis and liquid chromatography-mass spectrometry industry have made it a trusted partner to thousands of the scientists and lab analysts worldwide who are focused on basic research, drug discovery and development, food and environmental testing, forensics and clinical research.
With over 40 years of proven innovation, SCIEX excels by listening to and understanding the ever-evolving needs of its customers to develop reliable, sensitive and intuitive solutions that continue to redefine what is achievable in routine and complex analysis. For more information, please visit sciex.com
SCIEX social: @SCIEXnews, LinkedIn, and Facebook.
Program Manager, Brand, Public Relations and Social Media, SCIEX
+1 (508) 383-7163
M: +1 (508) 782-9484
AB Sciex is operating as SCIEX.
© 2018 AB Sciex. The trademarks mentioned herein are the property of the AB Sciex Pte. Ltd. or their respective owners. AB Sciex™ is being used under license.
For research use only. Not for use in diagnostic procedures.
The Destination for All Your Support Needs