Ion Sources

Mass Spectrometry Ionization Sources for Superior Performance

Effective analyte ionization is the critical first step in capturing high quality data from your mass spectrometry system. A quality ion source delivers more ions to the mass analyzer, increasing coverage over a wide analyte range.

SCIEX is renowned for pioneering groundbreaking mass spectrometry ion sources that are rugged, reliable and easily interchangeable, so you get the best performance and productivity from your mass spec system.

The Turbo V™ Source is our flagship ion source, delivering industry leading sensitivity, robustness and efficiency in ionizing compounds. Our ionization technology has continued to evolve with flexible options to cover a wider range of applications and flow rates. Explore our ion sources to find the one that is right for your lab and your workflows.

Behind Every Exceptional Mass Spec is an Exceptional Ion Source

Turbo V™ Source

The Turbo V™ Source is considered the gold standard in mass spec ionization. The patented orthogonal design delivers outstanding ionization efficiency and robustness across many applications, covering flow ranges of 5 uL/min to 3 mL/min. This renowned ion source acts as the foundation on which SCIEX mass spec systems are built and serves as the inspiration for many of the ion sources that followed.

From the Legend, A New Standard Is Born

IonDrive™ Turbo V Source

The IonDrive™ Turbo V source increases the capacity of the legendary Turbo V source, maintaining the simple orthogonal design but with higher capacity heaters and a wider sweet spot for enhanced sensitivity.

OptiFlow™ Turbo V Source

A revolution in microflow separations, the OptiFlow™ Turbo V source supports flow ranges from 1 to 200 uL/min, with a simple tool-free set-up and no manual adjustments needed to achieve optimal spray conditions.

DuoSpray Turbo V Source

Combining the two most common ionization techniques – electrospray ionization (ESI) and atmospheric pressure chemical ionization (APCI) – this source allows flexibility in method development and sample analysis on SCIEX TripleTOF® systems.

Additional Front End Components

OptiFlow™ Interface

A universal interface that allows fast switching between nanoflow, microflow and analytical flow regimes without the need to break vacuum on the mass spectrometer system.

SelexION® Differential Ion Mobility

Improve your assay selectivity, eliminating isobaric interferences and co-eluting contaminants, with this robust and powerful ion separation device.


Achieve fast, efficient and unique separation selectivity, and expand the reach of your mass spectrometer, with integrated capillary electrophoresis (CE) and electrospray ionization (ESI).