Up your game for ADC analysis with innovative analytical strategies presented by leaders in the field:

 

  • [Webinar] Untangle the charge heterogeneity information of an intact ADC
    Determine what is driving the change in the charge profile–the payload, the linker or the monoclonal antibody (mAb)–in this study presented by AstraZeneca

  • [Webinar] Tackle PTM identification with a streamlined platform method
    Elucidate critical post-translational modifications (PTMs) including glycosylation, deamidation and linker modifications on ADCs using the Intabio ZT system with Merck scientists

  • [Technical note] Bring the precision of MS identification to early development
    Get highly confident identification of critical quality attributes (CQAs) with an integrated icIEF-UV/MS solution that identifies low abundant PTMs at the intact protein level.

  • [Technical note] Access accurate drug-to-antibody ratio (DAR) measurement
    Learn about an easy-to-implement streamlined workflow that leverages high-resolution MS for accurate mass measurement of intact ADCs and powerful software tools for automated DAR calculation

  • [Technical note] Become confident in payload localization and characterization
    Discover a single injection workflow to enable new depths in peptide mapping analysis for accurate and detailed structural characterization of the payload