Liquid chromatography-tandem mass spectrometry (LC-MS/MS) can help both environmental scientists and regulators identify and quantify endocrine-disrupting chemicals (EDCs) at trace levels in water, soil, foods and other products.
Endocrine-disrupting chemicals are any chemical that interferes with the body's endocrine system, resulting in developmental, reproductive, neurological or immune deficiencies in humans and animals.1, 2 Many everyday household products contain these endocrine-disrupting chemicals. These include bisphenol A (which leaches from metal cans and plastic food containers), plasticizers (which leach from consumable products such as toys) and assorted flame retardants and pharmaceutical chemical compounds used in clothing and cosmetics.
Sources of EDCs in water include discharge of industrial waste to rivers, agricultural water runoff, air deposition, surface runoff and soil leachate, which often contaminate surface and groundwaters. Since conventional wastewater treatment methods may not adequately remove EDCs from wastewater,3 there is a real possibility that EDCs are present in water bodies.4-5
Numerous studies have reported the adverse effects of EDCs on aquatic ecosystems2 at various concentrations. There are also reports of reproductive disorders associated with EDCs,6-7 causing concern about EDC exposure through water consumption.
LC-MS/MS: Your gateway to identify and quantify EDCs in water
Considering the potential impact of EDCs, these chemicals have become a contaminant of emerging concern (CEC) for both regulatory agencies and the public. An LC-MS/MS approach can help you identify and quantify EDCs in water through high:
Sensitive detection of 4 endocrine-disrupting chemials at low parts-per-trillion levels
Accurately analyze the diverse chemical structures of PFAS, including GenX, using LC-MS/MS technology.
Get the selectivity, specificity and sensitivity you need to quantify PPCP compounds in the low parts-per-trillion range.
This easy-to-use accurate mass spectrometer system analyzes data faster using the power of SWATH® Acquisition.
This all-in-one software lets you acquire, process and analyze data, and even generate reports.
Use the MRM sensitivity of a triple quadrupole system to get even better identification and quantification.
Access more 17,000 compounds available at the click of a button.
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Detection of estrogens in aqueous and solid environmental matrices by direct injection LC-MS/MS | Download |
Analysis of endocrine disruptors, pharmaceuticals, and personal care products in river water | Download |