Enter a new era of sensitivity and LC-MS/MS innovation with the SCIEX Triple Quad™ 7500 LC-MS/MS System - QTRAP® Ready. GO BEYOND current limits of sensitivity, productivity targets, ruggedness and robustness challenges. Pioneer new discoveries with this innovation.
Experience extraordinary sensitivity gains from the SCIEX 7500 System. Start detecting the previously undetectable, and quantify at lower levels with impressive precision.
Expand your laboratory capabilities to test dirty and complex samples. The new D Jet™ Ion Guide will allow you to characterize analytes that were once masked by matrices.
Quantify more trace analytes at lower levels. Simplify sample prep, and inject less sample using the OptiFlow® Pro Ion Source. And also boost the transition of crucial ions into the system with the integrated E Lens™ Technology.
The SCIEX 7500 System delivers the highest level of sensitivity of all the SCIEX systems. Significant gains have been made in the analysis of key analytes that demand lower limits of quantification. The innovation in this product enables low level quantification of crude and complex samples to further your research. Plus expand and simplify your workflow with a linear dynamic range up to six orders magnitude.
The Turbo V™ Ion Source has evolved. The OptiFlow Pro Ion Source incorporated into the SCIEX 7500 System enables analytes in crude or complex samples to be detected. The OptiFlow Pro Source contains E Lens Technology, which improves the transfer of ions into the mass spectrometer. The modularity of the OptiFlow Pro Source enables the easy interchange from high flow to low flow and between ESI and APCI, quickly. Increase the sensitivity of your assay with the SCIEX 7500 System to gain a more accurate profile of your sample. The increased size of the orifice allows more ions into the mass spectrometer and the unique design of the D Jet Ion Guide retains and captures more of the ions from the ESI spray plume.
Move your workflow to this highly sensitive instrument and quickly see measurable gains in productivity. With innovation that enables you to test more samples, and detect trace compounds that previously could not be seen by any SCIEX system. The SCIEX 7500 System is powered by SCIEX OS Software, a platform for this next generation of mass spectrometers. Traditional software features and functions are complemented by visual aids and components to enable quick, accurate and confident data review.
Analyze and represent your data in a new and intuitive format. Control, acquire, analyze, interrogate and report, all on one software platform.
Enabling new levels of quantification
Using the SCIEX 7500 System, powered by SCIEX OS Software.
With a simple upgrade path this system can offer additional QTRAP functionality scan types. Pairing conventional MRM workflows and Enhanced Product Ion scans can enable improved confidence in acquired data. MRM3 workflows can push quantification levels through matrix interferences.
Get a stronger gradient around the orifice and protect your precious and limited sample. With the E Lens Technology, the power and efficiency of the SCIEX Turbo V Ion Source geometry is enhanced in the new OptiFlow Pro Source, which focuses transmission of the ESI plume into the orifice of the system.
Execute fast interchanges between high flow and low flow to adapt to your workflow needs. The OptiFlow Pro Source introduces a new modularity feature and incorporates the reliability and efficiency of the legendary Turbo V Ion Source.
Capture more of the ESI plume and retain more of the important ions than with previous technologies. The D Jet Ion Guide concentrates the samples and removes the gas molecules and neutral ions.
Attain lower levels of quantification compared to other SCIEX instruments. The precise and robust engineering of the ion rail allows consistent and reproducible analysis time after time, by focusing the crucial ions that you need for your workflow.
Chief Founding Scientist
Alturas Analytics, Moscow, ID
Manager, Science and Development
The rapid advancement of the drug pipeline demands sensitivity to allow a more complete pharmacokinetic characterization of low-dose drug candidates, below detection limits. The SCIEX 7500 System will enable pharmaceutical researchers to continue to explore lower dosage, higher efficacy compounds, and improve the efficiency of routine bioanalysis.VIEW TECHNICAL NOTES
In drug discovery, being able to make pharmacologically relevant measurements of drug candidates and evaluate the transporter at early-stage development is crucial when selecting drug safety profiles. The 7500 System offers you enhanced sensitivity to reduce compound concentrations, so it’s more biologically relevant. Download the technical note to see how you can get higher-quality data.VIEW TECHNICAL NOTES
Quantification of peptide/protein therapeutics in biological matrices is crucial for therapeutic development. Download the technical note that demonstrates a robust method using the SCIEX 7500 System to quantify a series of surrogate peptides in rat plasma at ultra-low LLOQs —5 to 39 fmol/mL.VIEW TECHNICAL NOTES
Quantifying intact peptide hormone analogs is challenging for because of low ionization and CID fragmentation efficiency related to the high molecular weights, low concentrations in matrices that require ultra-high assay sensitivity, and endogenous inferences from natural intact peptide hormones. Enter the SCIEX 7500 System. Read more about the sensitive LC-MRM method to quantify intact peptide hormones in rat plasma.VIEW TECHNICAL NOTES
Quantifying trace level cyclic peptides in biological matrices is extremely challenging. The SCIEX 7500 System can offer outstanding reproducibility, precision, accuracy, and linearity to ease these challenges. Download this ultra-sensitive MRM based cyclic peptide quantification workflow.VIEW TECHNICAL NOTES
There are important requirements for the quantitative measurement of host cell proteins (HCP) across the entire development paradigm. Learn about the targeted high sensitivity, analysis throughput, robustness and multiplexing capability approach using the SCIEX 7500 System.VIEW TECHNICAL NOTES
The complexity of the lipidome is very high with a huge diversity in lipid molecular species making comprehensive quantitative profiling challenging. Download this technical note to find out about a targeted MRM assay approach which enables quantification of a broad array of different lipids at the molecular species level using the SCIEX 7500 System.VIEW TECHNICAL NOTES
Quantitative robustness remains key, to ensure both large and small biological changes are accurately measured across large sample cohorts. The SCIEX 7500 System offers you high sensitivity as well as wide linear dynamic range for large scale targeted peptide quantification.VIEW TECHNICAL NOTES
Detecting and quantifying pesticide residues in food remains a moving target as food regulations drive the pursuit of lower limits of quantification. This work demonstrates the high sensitivity of the SCIEX 7500 System in quantifying 209 pesticides, easily achieving sub-ppb detection limits with a very small injection volume.VIEW TECHNICAL NOTES
The global scale of pesticide use, its impact on food safety and authenticity regulations have led to the need for sensitivity analysis that can achieve trace levels. Download the technical note to learn more about how the SCIEX 7500 System offers sensitivity, robustness and accuracy with 700 compounds achieving limits low as 0.2 ng/mL.VIEW TECHNICAL NOTES
Drinking water analysis is subjected to extremely low and rigid prescribed consent values (PCV) for determinands, including pesticides, pharmaceuticals and personal care products. In collaboration with Vitens Water Company, we demonstrated the sensitivity levels of the SCIEX 7500 System for low-level quantification across a relatively large suite of 431 determinands.VIEW TECHNICAL NOTES
As the cannabis market emerges globally, more stringent and lower level pesticide regulations may come into force. The SCIEX 7500 System shows its levels of sensitivity across a broad suite of regulated pesticides coupled with ruggedness and robustness for continued analysis of cannabis extracts.VIEW TECHNICAL NOTES
In a forensic laboratory, the ability to accurately quantify large panels of analytes in complex biological matrices over a wide range of concentration is challenging and often requires dilution of the samples to bring them within the calibration range of the instrument. In this technical note, the SCIEX 7500 System demonstrates exceptional performance in speed, linear dynamic range and sensitivity to overcome this challenge, quantifying a panel of 49 drugs in human whole blood.VIEW TECHNICAL NOTES
The detection and quantification of THC in drug screening can result in a high number of false positives since this analyte can be found in subjects passively exposed to cannabis. The SCIEX 7500 System offers you high sensitivity, robustness and performance to accurately quantify pg/mL levels of THC-COOH in oral fluid; without the need for derivatization.VIEW TECHNICAL NOTES
Yes! I want more info on the SCIEX Triple Quad™ 7500 LC-MS/MS System - QTRAP® Ready
The SCIEX clinical diagnostic portfolio is For In Vitro Diagnostic Use. Rx Only. Product(s) not available in all countries. For information on availability, please contact your local sales representative or refer to https://sciex.com/diagnostics. All other products are For Research Use Only. Not for use in Diagnostic Procedures. Trademarks and/or registered trademarks mentioned herein, including associated logos, are the property of AB Sciex Pte. Ltd. or their respective owners in the United States and/or certain other countries. The images shown may be for illustration purposes only and may not be an exact representation of the product and/or the technology. Echo and Echo MS are trademarks or registered trademarks of Labcyte Inc. in the United States and other countries, being used under license by SCIEX. Plates are available from Beckman Coulter Life Sciences. AB Sciex™ is being used under license. RUO-MKT-18-11611-A