The NanoLC™ 400 product series enables the full range of protein expression workflows that drive the identification of novel biomarkers to advance precision medicine research.
Ideal for the biomarker researchers digging deep in discovery or scaling up to validate their research findings, this front-end system is an innovative, flexible solution for a broad range of workflow needs.
Plug-and-play flow cartridges give you the flexibility to easily switch from the ultimate sensitivity of nanoflow LC-MS for discovery to high-throughput microflow LC-MS for validation.
The NanoLC 400 Series is available in two models, with patented pumps that make these systems among the most accurate nanoflow models on the market. Combined with industry-leading SCIEX mass spectrometers, the NanoLC Series provides high sensitivity, robustness and ease of use to support the latest in data-independent quantitative proteomics with SWATH® Acquisition.
When your sample is limited, and sensitivity is needed choose the NanoLC 415 for direct-to-column or trap-and-elute workflows. The NanoLC 415 is a complete package, providing an autosampler, solvent organizer, sample storage and cooling; plus a column oven - giving you the confidence that you will be up and running quickly.
The NanoLC 425 is an ideal HPLC system for labs performing a broad range of proteomics analyses. The additional pump gives you the power to dive deeper into your sample – with the ability to see more using 2D workflows. With the flexibility to have pre-set nano and microflow configurations, this 2-in-1 system is ideal for labs with diverse applications that need to actively switch between flow regimes. Like the NanoLC 415, this integrated system includes an autosampler, solvent organizer, sample storage and cooling; plus a column oven – helping your lab to realize its full potential.
Meeting the Needs for Every Proteomics Workflow
With single-gradient and dual-gradient models available - workflows from simple trap and elute to complex multi-dimensional separation are possible. The NanoLC 400 Series readily fits the ever-changing needs of your proteomics lab.
When Samples Are Precious
When you only have minimal amounts of sample, the NanoLC 400 Series can get you the high-quality identification and quantitation data you need for new biological insights.