AB Sciex is doing business as SCIEX. © 2010-2019 AB Sciex. The trademarks mentioned herein are the property of the AB Sciex Pte. Ltd. or their respective owners. AB SCIEX™ is being used under license. Beckman Coulter® is being used under license. Product(s) may not be available in all countries. For information on availability, please contact your local representative. For research use only. Not for use in diagnostic procedures.
iMethod Application for Mycotoxin Screening Version 1.2 for Cliquid Software

iMethod Application for Mycotoxin Screening Version 1.2 for Cliquid Software

iMethod Application for Mycotoxin Screening Version 1.2 for Cliquid Software

ExionLC™ System for UHPLC

ExionLC™ Series UHPLC

Analytical HPLC Solutions for LC-MS

Designed for seamless integration with SCIEX mass spectrometers, ExionLC analytical HPLC and UHPLC systems provide the speed, sensitivity, resolution, and reliability that you need for routine or complex LC-MS analysis.

Pick Your Model

ExionLC AC:
An affordable system that can handle a wide range of applications. With both HPLC and UHPLC capabilities the ExionLC AC is a reliable robust solution for routine analysis.

ExionLC AD (shown below):
The system combines near zero carryover, full UHPLC capabilities to provide world-class performance under the most demanding analytical conditions.

1. Wide Range of Flow Rates

0.0001 to 10.0 mL/min

2. HPLC/ UHPLC Performance

9,500 to 18,850 PSI

3. Ultralow Carryover

Innovative flow through design, ability to choose multiple rinse solutions

ExionLC
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4. High Throughput Capability

Up to 768 samples with 384 well MTP (expandable to 12 plates/trays with rack changer option)

5. Flexible Column Oven Choices

Choice of compact two-column oven, or six-column.

6. Optional Accessories

Multiplate autosampler (AD only), rack changer, and optical detectors

Key FeaturesExionLC ADExionLC AC
UHPLC/ HPLC Performance 18,500 PSI (1300 bar) 9,500 PSI (660 bar)
Ultralow Carryover 0.0015% maximum < 0.005%
Cooled Autosampler Direct cooling, 4 to 40°C
(under specified conditions)		 Direct cooling, 4 to 40°C
(under specified conditions)
Temperature Controlled Column Oven Room Temp. +5° C to 150°C, 2 column capacity
(AC column oven also compatible)		 Room Temp. -10° C to 85°C, 6 column capacity
(AD column oven also compatible)
Wide pH Range 1-9 (standard)
1-14 (optional)		 1-14

Pick Your Application

Customize Your ExionLC

Modular components allow you to update your system to keep pace with changing requirements. Add a column switching valve, two additional pumps and do on-line SPE. Add a PAL autosampler for automatic sample dilution or on-line microSPE.

Solvent Selector Valve

Allows you to select between two solvents per channel from up to 3 different pumps.

Rack Changer

Up to 12 additional cooled sample trays or vial racks to the AC or AD system.

Learn More >

Multiplate Autosampler

Expands capacity with 324 x 1.5 mL vials, or 6 microtiter plates in 96 or 384 formats.

Learn More >

PAL Autosampler

Increase productivity by adding a PAL RSI or PAL RTC Autosampler.

UV Detector

Time programmable wavelength switching allows detection sensitivity and selectivity.

Learn More >

PDA Detector

Excellent option for ID, quantitation, and purity analyses at trace levels.

Learn More >

Downloads & Resources

RUO-MKT-18-5633-B

Resources
Filter by Type:

Title Date
Fast Screening Method for 86 Forensic Analytes in Human Urine QTRAP 4500 05/10/2107
Time Course Study of Oxidation Stress Using SCIEX Solution for MAM with the X500B QTOF System 07/30/2019
Potency Analysis in Hemp and Cannabis Products 07/25/2019
LC-MS/MS Method for the Quantification of Budesonide in Human Plasma 07/02/2019
Looking to Expand Drinking Water Testing Capabilities 06/14/2019
Analysis of the Canadian Cannabis Pesticides List Using Both ESI and APCI Techniques 06/06/2019
Intelligently Designed SWATH Acquisition for Novel Psychoactive Substances (NPS) Detection in Whole Blood 06/04/2019
Quantitative Polarity Switching LC-MS/MS Method for Pesticides and PPCPs in Environmental Water Samples 06/02/2019
Analysis of Kratom’s Main Psychoactive Components 04/15/2019
Characterization of 2-AB Labelled Released N linked Glycans Using the X500B QTOF System 04/10/2019
Characterization of Intact Monoclonal Antibodies under Native and Reverse Phase Conditions 03/28/2019
Rapid Identification and Quantification of Novel Psychoactive Substances in Human Whole Blood Using SWATH® Acquisition 03/26/2019
Streamlined Unknown Screening for Postmortem Analysis 03/12/2019
Rapid Analysis of Genotoxic Nitrosamines by HPLC-MS-MS 02/25/2019
Achieving the California Pesticide Regulations in Cannabis Using Optimized APCI and ESI Techniques 02/20/2019
Time Course Study of Oxidation Stress Using SCIEX MAMvSolution with the X500B QTOF System 02/15/2019
Isotopically Resolved Subunit Analysis for Tracking Protein Therapeutic Stress Studies 02/02/2019
Food-Fraud-Authenticity 02/01/2019
The Overview of LC-MS Quantitative Solutions for Biotherapeutic Analysis 01/23/2019
Analysis of the Massachusetts Cannabis Pesticides List Using the SCIEX QTRAP 6500+ System 01/22/2019
ExionLC AD Specifications 01/18/2019
ExionLC Series Overview 01/02/2019
ExionLC AC Series Specifications 12/26/2018
ExionLC Series Brochure 12/26/2018
Meeting California Cannabis Testing Requirements Using SCIEX LC-MSMS 12/26/2018
Highly Selective Bioanalytcal Quantitation Method for Analysis of (R)-Amlodapine and (S)-Amlodapine Enantiomers in Human Plasma using LC-MS/MS 12/06/2018
Separation of Bile Acid Isomers with Differential Mobility Spectrometry 12/03/2018
Isotopic Resolution of Chromatographically Separated IdeS Subunits Using the X500B QTOF System 08/30/2018
Modernizing the Forensic Lab with LC-MS/MS Technology 08/14/2018
X500R: Profiling and Identification of Hop-Derived Bitter Compounds in Beer using LC-HR-MS/MS 07/31/2018
Quantitation of Dicamba and Acid Herbicides in Agricultural Field Samples on SCIEX QTRAP 6500plus System 07/02/2018
Essential LC-MS Performance Kits 06/01/2018
User Guide: HPLC System Site Planning Guide (EN) 04/30/2018
Intact Analysis of Antibody Drug Conjugates 02/01/2018
X500B: Glycosylated and Deglycosylated Subunit Analysis of Antibody Drug Conjugates 12/20/2017
Immunoaffinity-High Resolution Accurate Mass Assay for Pre-Clinical Quantification of Trastuzumab in Rat Plasma 12/17/2017
Forensics Targeted Analysis using X500R 11/30/2017
Elevating the Forensic Laboratory Performance 11/30/2017
High Throughput Platform for Confident Identification and Quantitation of Organic Explosives 11/27/2017
Increased Throughput for ADME Studies Using the SCIEX ExionLC™ AD UHPLC System 11/15/2017
Efficiently Designed Workflows Provide Accurate Results in Forensic Analysis of THC-COOH in Hair 11/06/2017
mAb Oxidation Analysis using X500B and Peptide Mapping 10/02/2017
Detection of Intact Antibody Impurities on the SCIEX X500B QTOF 09/18/2017
Quantitation of Oregon List of Pesticides and Cannabinoids in Cannabis Matrices by LC-MS 08/01/2017
SCIEX Success Programs Listing 07/26/2017
Quantitation of Microcystins and Nodularins in Water Samples 05/23/2017
Routine Workflow for Comparability Assessment of Protein Biopharmaceuticals 04/04/2017
Comparative peptide mapping between two manufacturers of Trastuzumab using the X500B QTOF System 04/04/2017
Trastuzumab-PepMap-SWATH-comparison 04/04/2017
Metabolite Identification of Payload Species of Antibody Drug Conjugates with Noncleavable Linkers using MetabolitePilot 2.0 Software and TripleTOF 6600 System 03/16/2017
Therapeutic Peptide Catabolite Identification using MetabolitePilot 2.0 Software and the TripleTOF 6600 System 03/16/2017
Cannabis for Per Se Law Testing in Whole Blood using theSCIEX Triple Quad QTRAP 4500 LC-MS/MS System 03/06/2017
Rapid and Sensitive Analysis of Antibiotics in Children's Urine Using the X500R QTOF System 03/01/2017
Analysis of Streptomycin and its Metabolite in Milk Using the SCIEX Triple Quad 3500 System 01/01/2017
Quantitation of Chloramphenicol in Milk using SCIEX Triple Quad 3500 LC-MS/MS System 01/01/2017
Rapid, Sensitive, Quantitation method for Chloramphenicol in Meat using SCIEX Triple Quad 3500 LC-MS/MS System 01/01/2017
Using MS/MS with SWATH Acquisition for Forensic Designer Drug Analysis and SCIEX X500R QTOF System and SCIEX OS Software 12/07/2016
Robust and Generic Method for Quantification of Monoclonal Antibody Therapeutics in Biological Matrices 11/01/2016
LC-MS/MS Analysis of Emerging Food Contaminants Detection of Glyphosate in Food Samples using QuPPe-LC-DMS-MS/MS 09/01/2016
X500R - A Compendium of Related Research Applications 06/01/2016
X500R: Identification of Artificial Dyes in Food Using LC-HR-MS/MS Non-Target Screening 05/01/2016
X500R: Identification of Hop-Derived Bitter Compounds in Beer Using LC-HR-MS/MS 05/01/2016
Perfect Balance to Elevate your Lab’s Performance Using the X500R QTOF System and SCIEX OS Software to Identify and Quantify Food Residues 04/30/2016
Quantitation of Cannabinoids and Pesticides in Cannabis Products Using the Triple Quad 3500 LC-MS/MS System 04/20/2016
Identification and Quantification X500R 04/12/2016
Unknown Screening X500R QTOF 04/12/2016
Elevate Lab Performance Using X500R and SCIEX OS to Identify and Quantify Food Residues 04/10/2016
Elevate Lab Performance Using X500R and SCIEX OS Software to Quickly Identify Unknowns in Food Samples 04/10/2016
Forensic Identifications and Quantification Workflows Delivered on a Revolutionary Designed QTOF and SCIEX OS Software 04/04/2016
Efficient Forensic Toxicological Screening and Quantitation Workflow Using QTOF LC-MS/MS System 03/01/2016
Fast and Simultaneous Analysis of Ethanol Metabolites and Barbiturates using QTRAP 4500 LC-MS/MS System 02/01/2016
User Guide: ExionLC PDA Detector Operator Guide (EN) 10/15/2015
LC-MS/MS Analysis of Emerging Food Contaminants (Perfluoroalkyl Acids) 10/01/2015
LC-MS/MS Analysis of Emerging Food Contaminants (6500+) 10/01/2015
Rapid and Sensitive Analysis of a 93-Compound Forensic Panel in Urine using the QTRAP/Triple Quad 4500 LC-MS/MS System 10/01/2015
User Guide: ExionLC System Software User Guide 09/30/2015
ExionLC PDA Detector Specifications 09/20/2015
ExionLC AC Injection Linearity, Precision and Carryover 09/15/2015
User Guide: Systeme ExionLC Guide de Securite 07/31/2015
User Guide: ExionLC Degasser Operator Guide (FR) 05/31/2015
User Guide: ExionLC Degasser Operator Guide (EN) 05/31/2015
Exion LC AD Multiplate Autosampler 05/20/2015
ExionLC Rack Changer Specifications 05/20/2015
ExionLC UV Detector Specifications 05/20/2015
User Guide: ExionLC AC System Hardware User Guide (EN) 04/30/2015
User Guide: ExionLC AC System Hardware User Guide (FR) 04/30/2015
User Guide: ExionLC AD System Hardware User Guide (EN) 04/30/2015
User Guide: ExionLC AD System Hardware User Guide (FR) 04/30/2015
User Guide: ExionLC AD Multiplate Sampler Operator Guide (FR) 04/30/2015
User Guide: ExionLC PDA Detector Operator Guide (FR) 04/30/2015
User Guide: ExionLC Rack Changer Operator Guide (EN) 04/30/2015
User Guide: ExionLC Rack Changer Operator Guide (FR) 04/30/2015
User Guide: ExionLC UV Detector Operator Guide (EN) 04/30/2015
User Guide: ExionLC UV Detector Operator Guide (FR) 04/30/2015
User Guide: ExionLC AD Multiplate Sampler Operator Guide (EN) 04/30/2015
Routine Methodologies for Detection of Low Abundance Attributes 03/02/2015
exionlc-featured-imgleft-1col-comp

LC Solutions Tailored to Meet Your Needs

Your lab has unique analytical requirements and our goal is to provide LC-MS solutions tailored to meet your needs. The ExionLC™ Series of robust and reliable HPLC/UHPLC systems offers a wide range of performance and flexibility.

Read More >
exionlc-icontop-4col-comp
Pharma and Biopharma

Pharma and Biopharma

Make confident decisions faster, resulting in more efficacious, safer therapeutics.

Learn More
Food and Beverage Testing

Food and Beverage Testing

Solutions to test and protect our global food and beverage supply.

Learn More
Forensics Testing

Forensics Testing

Complete forensic drug testing solutions to help you uphold result integrity.

Learn More
Life Science Research

Life Science Research

Accelerate the pace of your research to identify key genes, proteins, lipids and metabolites.

Learn More
exionlc-intro-icontop-4col-comp

The Power of UHPLC/HPLC Performance

Backed by over 40 years of trusted LC-MS innovation and service, the ExionLC provides you with the versatility, reproducibility and robustness to tackle the toughest applications, from method development to routine analysis, 24/7.

ExionLC AD

Quantitate with Confidence

ExionLC AD combines accurate injection volumes with near zero carryover to make quantitation a breeze.

Read the Tech Note

Unrivaled Reproducibility

Flow rate precision < 0.06% and accuracy of less than 2% gives you the analytical accuracy and precision you need day in and day out.

Read the Tech Note

No Fuss Upgrades

Expand your capabilities with a wide range of options that allow you to simplify method development, automated sample prep or increase throughput.

See the Presentation

ExionLC AC

More Performance, Less Cost

The ExionLC AC delivers with its affordable price and HPLC /UHPLC separation capabilities.

Read the Tech Note

Better Results, Faster

Reproducible retention times combined with sensitive, accurate quantitation gives you results you can trust.

Read the Tech Note

Ultimate Flexibility

ExionLC can support multiple components, and configurations to meet the changing demands of your laboratory.

See the Presentation
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AB Sciex is doing business as SCIEX. © 2010-2019 AB Sciex. The trademarks mentioned herein are the property of the AB Sciex Pte. Ltd. or their respective owners. AB SCIEX™ is being used under license. Beckman Coulter® is being used under license. Product(s) may not be available in all countries. For information on availability, please contact your local representative. For research use only. Not for use in diagnostic procedures.