iMethod Application for Melamine and Cyanuric Acid in Milk Products Version 1.0 for Cliquid Software
For research use only. Not for use in diagnostic procedures.
Determine melamine and cyanuric acid in milk using solid phase extraction (SPE) cleanup and fast LC/MS/MS analysis
Recent issues with melamine contamination in wheat gluten- and milk-based ingredients from China have highlighted the need for both food manufacturers and regulatory agencies to utilize fast and accurate analytical techniques like LC-MS/MS to proactively ensure product safety. This verified method for melamine and cyanuric acid analysis in milk samples utilizes a single solid phase extraction (SPE) cleanup step to remove matrix components for determination by LC-MS/MS with a run time of less than 10 minutes and limits of quantitation below 1 μg/kg.
Two MRMs are used per compound with ion ratios calculated to provide an extra degree of confirmation.