 
                For research use only. Not for use in diagnostic procedures.
Determine melamine and cyanuric acid in milk using solid phase extraction (SPE) cleanup and fast LC/MS/MS analysis 
Recent issues with melamine contamination in wheat gluten- and milk-based ingredients from China have highlighted the need for both food manufacturers and regulatory agencies to utilize fast and accurate analytical techniques like LC-MS/MS to proactively ensure product safety. This verified method for melamine and cyanuric acid analysis in milk samples utilizes a single solid phase extraction (SPE) cleanup step to remove matrix components for determination by LC-MS/MS with a run time of less than 10 minutes and limits of quantitation below 1 μg/kg.
Two MRMs are used per compound with ion ratios calculated to provide an extra degree of confirmation.
To learn more, please view this flyer: A Rapid iMethod™ Application for the Analysis of Melamine and Cyanuric Acid in Milk Products
Status: Available
 
        Reduce development time
| Activity | Using an iMethod Application | Traditional Method Development | 
|---|---|---|
| Complete Test Protocol Documentation | Included | Weeks–Months | 
| Sample Prep Techniques | Included, with examples and references | Weeks–Months | 
| Optimized MS/MS Acquisition Parameters | Included | Weeks–Months | 
| LC Instrument Parameters with Retention Times | Included | Days–Weeks | 
| Integration (Quantitation) Parameters | Included | Days | 
| Reporting Templates | Included | Days | 
| LC/MS/MS Library Spectra | May be included. Stand-alone libraries are also available. | Weeks–Months | 
| Staff Training – Software | Simple Cliquid® Software interface, no additional training | Traditional MS Software and review procedures – Days | 
| Method Validation | Weeks. Validation templates and support available | Weeks–Months | 
| Complete Test Development and Deployment | Weeks | 6–12 months |