STR Analysis

Identify alleles even in the presence of enzyme stutter and the plus Adenosine artifact

STR Analysis

Tandem repeat regions in DNA sequences are widespread throughout the human, plant and microbe genomes and show sufficient variability among individuals that they have become important in genetic mapping and linkage analysis. These repeat regions of DNA are typically classified into several groups depending on the size of the repeat region. Minisatellites (variable number of tandem repeats, VNTRs) have core repeats with 9-80 bp, while microsatellites (short tandem repeats, STRs) contain 2-7 bp repeats. STR markers are very abundant and well-distributed throughout the genomes, located approximately every 10-15 kb. STRs have become one of the most widely used genomic markers for identity testing and gene mapping due to their abundance and high degree of heterozygosity. Ideal STR polymorphisms amplify well under standard conditions, have a low amplification background, are easy to score and are highly informative. The GenomeLab™ Software provides accurate and high precision sizing of these amplified fragments including automated allele and locus identification. You can identify alleles even in the presence of enzyme stutter and the plus Adenosine artifact.

STR Data Analysis

Alleles may be identified by size or a combination of size and color allowing STRs to be identified from the same simplified set up.

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All parameters associated with the results are at your fingertips, allowing data to be reviewed with ease. Electropherograms may be further stacked and overlaid to facilitate data comparison.

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The GeXP Series delivers sophisticated set of tools for managing and reviewing data, with sorting and filtering tools that operate on a set of over 100 independent properties. Individual results can be mapped to your personal preference to automatically review the data.

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