The SCIEX clinical diagnostic portfolio is For In Vitro Diagnostic Use. Rx Only. Product(s) not available in all countries. For information on availability, please contact your local sales representative or refer to https://sciex.com/diagnostics. All other products are For Research Use Only. Not for use in Diagnostic Procedures.
Trademarks and/or registered trademarks mentioned herein, including associated logos, are the property of AB Sciex Pte. Ltd. or their respective owners in the United States and/or certain other countries.
© 2020 DH Tech. Dev. Pte. Ltd.
For research use only. Not for use in diagnostic procedures.
LightSight Software is the ultimate tool for finding metabolites. In a few simple steps, highly-optimized acquisition methods can be created to detect metabolites with unprecedented effectiveness. This allows for open-access metabolite identification experiments on a QTRAP® System with minimal operator training. The streamlined acquisition process gives ADME scientists highly-relevant, rapid results. LightSight Software makes the work of identifying metabolites more efficient than ever, with a workspace that supports quick, effective decision-making. LightSight Software has an exceptionally clear data display that eliminates tedious visual comparison of printouts. Non-mass spectrometric analog data (e.g., UV- or radioactive-detector chromatograms) can be simultaneously analyzed in LightSight Software v2.2.1, so that MS-based structural information can be correlated with quantitative analog data.
Increased metabolite detection: LightSight Software creates highly-optimized acquisition methods that allow for increased metabolite detection. In a few simple steps, acquisition methods for metabolite detection are constructed with unprecedented effectiveness. This allows for open-access metabolite identification experiments on a QTRAP System with minimal operator training. The streamlined acquisition process gives ADME scientists highly-relevant, rapid results. LightSight Software creates compound-specific, predicted MRM/Information-Dependent Acquisition methods (pMRM-IDA), in which metabolite detection in increased significantly over traditional theoretical MRM-IDA methods. Detect even lower-level metabolites with MRM-specificity and sensitivity, simultaneously collecting high-quality MS/MS data on any detected peaks with the QTRAP 5500 System.
Multiple survey scan methods: LightSight Software v2.2.1 enables you to easily create methods for the QTRAP 5500 System with multiple survey scans in a single step. Multiple survey scan methods are especially useful for sensitive detection of phase II conjugated metabolites. The hardware functionalities of the QTRAP 5500 Systems are fully enabled by LightSight Software v2.2.1; the software can be used to create data acquisition methods based on the drug structure, for seamless analyis and data mining. Sensitive, triple-quadrupole-mode survey scans, such as neutral loss or precursor ion, can be coupled with highly-sensitive, full-scan MS/MS data for structural characterization.
Non-mass spectrometric analog data (e.g. UV- or radioactive-detector chromatograms) can be simultaneously analyzed in LightSight Software v2.2.1, so that MS-based structural information can be correlated with quantitative analog data. This unique combination of features makes high productivity metabolite identification possible using the QTRAP 5500 System with LightSight Software.
Intuitive method building: LightSight Software is the right tool regardless of how you perform MS/MS acquisition. MS/MS data is easily obtained, either simultaneously with survey data, using Information-Dependent Acquisition (IDA), or in a separate run, after analyzing the survey data. The Acquire MS/MS Data wizard creates sophisticated, multi-period, multi-experiment methods that often collect MS/MS data for all of a compound's metabolites in a single injection.
Simple, clear data processing: LightSight Software identifies metabolites more efficiently than ever, with a workspace that supports quick, effective decision-making. Extracted ion chromatograms (XICs) of the sample overlaid with the control make chromatographic peaks instantly distinguishable from noise. Adjacent and aligned displays of the parent and metabolite MS/MS spectra make spectral similarities and differences immediately obvious. LightSight Software has an exceptionally clear data display that eliminates tedious visual comparison of printouts. And now, in Version 2.2, processing parameters can be saved, which makes analysis of large sets of data easier and faster than ever.
Intuitive design, powerful help: LightSight Software is designed with a simple, intuitively-appealing, and easy-to-use interface, so that your time is spent studying metabolism, not software. Exhaustive sets of biotransformations are built into the software, or custom biotransformation sets can be designed based on what is already known about your candidate compound. Predicted MRM (pMRM) methods can be created automatically using LightSight Software and loaded directly to the QTRAP Instrument for rapid analysis. The ability of pMRM to predict a comprehensive list of transitions allows for the detection of a number of interesting metabolites. Next- generation metabolite in silico prediction via LightSight Software is a perfect complement to the capabilities of the QTRAP 5500 System and allows even novice metabolite investigators to achieve complete results easily.
Powered by Clearcore MD™ Foundation Software: LightSight Software is the first application to be powered by the Clearcore MD™ Foundation Software, providing solid, easy-to-use software applications.
A new password has been sent to your email.
You have added a user.
Unfortunately the serial number you provided shows as inactive in our database. Would you like to submit the case anyway?
This serial number could not be found. Would you like to submit the case anyway?
Your password has been updated.
Your account is now created.
A verification link has been sent to your email.
A new password has been sent to your email.
Your insturment has been removed.
Your privacy settings are now updated.
Unfortunately the serial number you provided shows as inactive in our database. Please open a support case here if you require more assistance.
Software has already been registered to another instrument. Please check your AID and try again.
If you want to change the License Key to another instrument, please submit a new case.
Software has already been registered to the instrument selected.
Please check your instrument's software by going to the Instruments page and selecting the instrument in your "My Instruments" section. Here you will see a Software tab where you can view your instrument's software information.
You can also go to the Registered Software page to view software associated with your instrument(s).
If you are not finding what you are looking for, please submit a new case.