Defensible high-throughput screening and quantitation of drug compounds in forensic samples.
RUO-MKT-18-3393-A For Research purposes only. Not to be used in diagnostic procedures.
There were an estimated 183,000 drug-related deaths worldwide in 2012, according to the United Nations Office on Drugs and Crime 2014 World Drug Report. This shocking statistic is even more alarming — up to 324 million people have used an illicit drug at least one in the previous year, that’s 7% of the global population!
Those statistics demonstrate it is critical for law enforcement agencies to undertake forensic drug testing in an efficient manner which ensures the highest levels of accuracy and turnaround.
Mass Spectrometry is paramount in delivering justice! LC-MS/MS has become the industries preferred method due to its sensitivity, selectivity and accuracy over conventional methods such as GC, GC-MS and U.V detection. Whether you are doing ROUTINE toxicology tests or investigative work at the forefront of forensic research then there are excellent and reliable solutions using our QTRAP® or QTOF technologies. The X500R QTOF system powered by our quick to learn and intuitive software SCIEX OS can redefine how you analyze your routine forensic drug screening sample, whereas our 6500 QTRAP® or 6600 TripleTOF® can assist you with research and method development.
With a comprehensive library of over 1700 forensic drug compounds, screening can be quicker and far more accurate than ever before.
Today, LC tandem mass spectrometric analysis (LC-MS/MS) is the preferred method of analysis for forensic over traditional analysis techniques – both for screening and confirmation purposes. Here are some advantages LC-MS/MS provides over conventional methods:
Better compound detection sensitivity for significantly lower levels than current cut-off levels
Faster time to results, with less sample prep and no derivatization
Save time and money with multiplexing capabilities to analyze for many compounds in a single analysis
Ability to simultaneous quantify and identify many drug targets in various sample matrices such as saliva, urine, blood or hair samples
Further optimization of the LC-Method can seriously increase sample throughput and efficiency of your forensic drug testing lab
The two images above show that method optimization can dramatically reduce your sample run time. In the above examples, by reducing the LC gradient profile to just 2.58 mins a batch of 17 samples can be completely acquired in less 44 minutes. With further LC gradient optimization, the sample run time can be reduced to just 2.08 mins; thus, a batch of 17 samples were completely acquired in 35.23 mins. This data was acquired on the X500R QTOF system, powered by our quick to learn and intuitive software SCIEX OS.
SCIEX has the solution for your forensic drug screening, we have application notes and expertise in the analysis of Amphetamines, Antidepressents, Benzodiazapines, Synthetic Cannabinoids, Cathionones, Opiates Phenethylamines, Piperazines, Tryptamines and more.