Metabolomics

Empowering metabolomics researchers: catalyzing discoveries that transform lives

From research to translational medicine

Illuminating metabolic pathways

Metabolomics is crucial for understanding diseases and searching for potential biomarkers. By measuring metabolomics changes due to various factors—environment, lifestyle, diseases and treatments, for example—researchers can reveal insights into specific cellular processes. This understanding informs the onset and progression of diseases such as diabetes and cancer, facilitating patient stratification and precision medicine.

The number and type of small molecules that make up the metabolome for any given biological system are vast and complex. The metabolism of any organism is constantly changing, using and producing various molecules for an extremely wide diversity of cellular processes. The incredible number and diversity of small molecule metabolites involved in these reactions makes metabolomics studies enormously challenging.

Workflow

Targeted identification and quantitation

Set your sights on specific metabolites

Targeted metabolomics involves selecting and quantifying the metabolites and pathways of interest. Dive into SCIEX solutions for targeted metabolomics. Beyond triple quadrupole technology, our portfolio offers a wealth of MS/MS capabilities and front-end enhancements for unparalleled sensitivity, accuracy and precision. Discover how our solutions can help you:

  • Quantify metabolites and uncover pathways with highly sensitive and specific approaches
  • Identify and quantify metabolites with confidence through robust, reproducible analyses
  • Explore the depths of the metabolome with enhanced sensitivity and dynamic range
  • Enable comprehensive target characterization and structural elucidation with election associated dissociation (EAD) technology

Bile acid analysis

Dive into the world of bile acids and explore how the latest advancements in SCIEX mass spectrometry are revolutionizing their quantitative analysis and structural characterization. 

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Workflow

Discovery and translational metabolomics

Explore the uncharted realms of the metabolome

Untargeted metabolomics seeks to identify metabolites and turn them into biological answers. SCIEX solutions focus on generating comprehensive datasets containing large amounts of information through unique, modern approaches such as data-independent acquisition (DIA) using SWATH DIA or alternative fragmentation using electron-activated dissociation (EAD). Discover methodologies and solutions for identifying new and unknown metabolites and comparatively quantifying across complex samples and matrices. Find out how our solutions can help you:

  • Explore the metabolome with high sensitivity, expanding metabolite coverage
  • Enable fast, accurate identification and quantitation using sensitive, robust and reproducible technologies
  • Perform large-scale experiments with powerful, high-throughput workflows and solutions
  • Enable comprehensive target characterization and structural elucidation with election associated dissociation (EAD) technology

Workflow

High-throughput metabolite screening

The Echo® MS+ system delivers high-quality data, analytical flexibility and high sample throughput to accelerate your metabolomics studies. When sample numbers are high, utilize ejection rates of up to 1 sample per second to get same-day results. The Echo® MS+ system is a complete solution for high-throughput analytical workflows, from sample preparation to data reporting. Experience capabilities such as:

  • Quantitation of target analytes with accuracy and speed
  • Support for a high-throughput automated end-to-end workflow
  • Minimized sample consumption with ejection volumes of 2.5 nL
  • Compatibility with QTRAP 6500+ and ZenoTOF 7600 systems

Workflow related components

Accurate MS with the ZenoTOF 7600 system

Get qualitative flexibility combined with quantitative power. With the ability to detect more low-level metabolites than ever before, the ZenoTOF 7600 system offers new, precise perspectives on the metabolome.

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Targeted metabolomics with the SCIEX 7500 system

Enable detection and quantitation of the widest scope of chemical compounds. Improved polarity switching and MRM3 speeds allow faster chromatography and better throughput. Quantitative MRM workflows and qualitative QTRAP system scans in the same injection maximize throughput.

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Targeted metabolomics with the QTRAP 6500+ system

Enable detection and quantitation of the widest scope of chemical compounds. Improved polarity switching and MRM3 speeds allow faster chromatography and better throughput. Quantitative MRM workflows and qualitative QTRAP system scans in the same injection maximize throughput.

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High-throughput mass spectrometry with the Echo® MS+ system

Get high-quality data, analytical flexibility and high sample throughput so you can make informed decisions. The Echo® MS+ system is a complete solution that removes bottlenecks in high-throughput analytical workflows, from sample preparation to data reporting.

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ExionLC AE system

Discover reproducibility, reliability and carryover performance to match your quantitative workflows. Experience dependability you can count on from injection to injection and batch after batch.

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SCIEX OS software

Unleash the analytical power of a next-generation software platform for data acquisition and processing.

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Service

Keep your instruments performing at their peak with multiple options for response time, repair coverage and maintenance.

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Thought leaders

Extraordinary science

Step into the captivating realm of groundbreaking science with biomedical and omics researchers using the ZenoTOF 7600 system.

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Thomas Hankemeier

Professor of Analytical BioSciences, Leiden Academic Centre for Drug Research (LACDR)

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Omics related content

Lipidomics

Simplify lipidomics approaches and accelerate your research. Discover, identify and quantify thousands of lipids with confidence. Overcome the challenges of diverse lipid classes and molecular compounds with enhanced selectivity and powerful, time-saving solutions.
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Proteomics

Explore the depth and complexity of the proteome. Accelerate your understanding of biology with streamlined data acquisition, processing and interpretation solutions that can be applied to a single sample or on an industrial scale across large cohorts.
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Food omics

Learn about large-scale omics profiling from field to fork and beyond. Explore a comprehensive approach to food and nutrition analysis.
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SCIEX Omics community

Chat with your peers about how to get the most out of your proteomics, metabolomics and lipidomics studies.

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