Spotlight on: SCIEX OS software

What is SCIEX OS software?

SCIEX OS software is an integrated software platform solution that delivers data integrity, seamless usability and efficiency gains for quantitative and qualitative mass spectrometry workflows, alike. Built on advanced and sophisticated algorithms, SCIEX OS software facilitates instrument control and automated data processing, simplifying laboratory workflows and empowering swift, well-informed decision-making. It caters to both new users and seasoned mass spec professionals, helping laboratories maintain compliance through audit trails and role-based access, while allowing scientists to focus on discovery by automating tedious tasks. At least one customer has reported saving 20% of the time typically spent reviewing data.

What makes SCIEX OS software so well liked?

With AI-driven quantitation, seamless instrument integration, and compliance-ready features, scientists in both research and regulatory environments can work faster, smarter, and more securely. With built-in data integrity features that allow customization of functionality specific to each lab’s compliance and data security requirements, scientists of all disciplines will achieve data integrity across every run, on every system. Some of the features that customers really love are: easily importing of libraries, opening and editing multiple MS or LC methods at the same time, being able to create custom fields in the batch that can then be used for processing in formulas or calculated columns later, and streamlining calibration curve review with the Automatic Outlier Removal feature.

How is SCIEX OS software impacting the LC-MS world?

SCIEX OS software is transforming how laboratories operate across many different LC-MS applications from pharmaceutical discovery and development, to food safety and testing, to PFAS testing, to clinical research domains. Its latest version introduces automated compound optimization, high-resolution printing for regulatory submissions, and advanced decision rules that reduce manual intervention. With Windows 11 support, laboratories are ready to meet any IT security policies and to reduce cybersecurity risks. SCIEX OS software also makes it easy to communicate globally across different time zones by translating the user interface into many languages. So far support for Chinese, Japanese, Korean, German, Italian, French, Spanish, Portuguese, and English is available. That’s a lot of ways to say hello!

How is SCIEX OS software helping laboratories overcome key challenges?

SCIEX supports new users with the intuitive design of SCIEX OS software and a hands-on virtual trial of the full, complete solution (see the resources section for link), as well as guided onboarding resources like navigation guides and example workflows. For existing users, SCIEX OS software provides tools such as automated method development, intelligent decision rules, and a centralized administration console to streamline operations and reduce manual effort. And since we understand that laboratory infrastructure becomes increasingly interconnected, SCIEX OS software offers three APIs that provide connectivity to the software and data: Control, Processing, and Data APIs. Continuous improvements are driven by user feedback and internal training, ensuring labs stay productive, confident, and supported every step of the way. For more tips and tricks, see the resources section below.

Key benefits of SCIEX OS software

Automatic compound optimization: SCIEX OS software automates parameter optimization for large compound sets, and includes support for HPLC vials and 96- or 384-well plates. This reduces manual setup and improves throughput.
Decision rule automation: SCIEX OS software enables logic-based decision rules that trigger intelligent actions during batch acquisition, such as real-time corrections and sample submission decisions. This enables more consistent flagging than any manual processes.
Windows 11 compatibility: SCIEX OS software is compatible with Windows 11, helping labs meet IT security policies and reduce cybersecurity risks.
OCR-ready printing: SCIEX OS software supports high-resolution, vector-format printing with embedded text for optical character recognition (OCR). This improves GLP/GxP compliance and reduces manual data entry.
Unified support across mass spectrometry platforms: SCIEX OS software eliminating the need for multiple software environments by supporting our ZenoTOF and X500 series of QTOFs instruments, as well as SCIEX 4500, 5500, 6500, 7500 series systems.
21 CFR Part 11 compliance: Incorporates electronic audit trails, signatures, and detailed security configurations to support GxP and 21 CFR Part 11 regulations. SCIEX OS software offers the flexibility to tailor and deploy security policies that help meet the requirements of each unique laboratory.

Explore more below:

Suspect screening data processing workflow for the analysis of pesticide in food using SCIEX OS software

This technical note describes a suspect screening data processing workflow in the SCIEX OS software for the non-targeted analysis of pesticides in fruits, vegetables and herbs.

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Automated peptide fragment ion selection and summation for streamlined HRMS quantitative workflows

This technical note demonstrates an automated fragment selection workflow to streamline HRMS-based peptide quantitation using SCIEX OS software on the ZenoTOF 8600 system.

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Custom calculation and filtering packages for SCIEX OS software based on EU guidelines

This technical note describes the use of pre-built custom calculation and flagging packages to simplify and streamline SCIEX OS software data processing.

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SCIEX OS software feature guide

Moving forward together from Analyst to SCIEX OS software

Understand why the transition from Analyst software to SCIEX OS software is about building on your expertise with smarter, more agile tools.

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SCIEX OS software tips and tricks

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Solution

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