BioPhase 8800

capillary electrophoresis system

Take Charge

The SCIEX BioPhase 8800 is a multi-capillary electrophoresis system that enables biopharma scientists to run multiple samples in parallel, accelerating the development and execution of sensitive, high-throughput analytical methods. The increased throughput and reproducibility of the system minimizes bottlenecks in the drug development pipeline, helping shorten time to market.

BioPhase 8800 System

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Multiply your results. Multiply your success. Accelerate the development of your biotherapeutics.

Innovated from the ground up, the SCIEX BioPhase 8800 helps biopharmaceutical labs take charge of their development pipelines.

Scientists can now assess molecular liabilities more quickly, allowing rapid developability assessment to streamline the selection of candidates to be progressed into an effective therapy.

Run more samples, and more molecules, on a single system through not one, but eight capillaries in parallel.

Existing approaches to detect and characterize changes during development of monoclonal antibodies (mAbs), next-generation therapeutics, and gene therapies are challenged to deliver the detailed information you need, in the time you need it.

The SCIEX BioPhase 8800 system facilitates parallel processing of eight samples simultaneously, while retaining the capability to deliver sensitive CE-SDS, and CIEF analysis enabling uncompromised accuracy for large sample sets and faster time to answers.

Overcome QTOF MS/MS duty cycle deficiencies

Empower

Take on multiple molecules, multiple applications in less time - all on a single platform.
Tunable fragmentation of all molecule types

Accelerate

Shorten time to market with high-throughput, 8 capillary analytics.
MS/MS scan rates of up to 133Hz

Simplify

With user friendly software and pre-packaged reagents, running applications on the SCIEX BioPhase 8800 is quick and easy.

Explore the BioPhase 8800 system.

Delivering consistent, comparable and compliant data at scale across the biologic development continuum, the SCIEX BioPhase 8800 provides high-throughput, high sensitivity analysis for bioprocessing, analytical development and QA/QC, all in one system.

7500 system 7500 system
Compatability
Acoustic Droplet Ejection (ADE)

Compatability

Convenient 96-well plate format compatible with standard liquid handling systems.

Robustness
Robustness

Robustness

Designed for robustness, hardware and software advances ensure repeatability and increased reliability.

Flexibility
Echo MS probe

Flexibility

Flexible to your workflow requirement, switching between UV and UV-LIF detection is simple and seamless. Integrated detection modules make it easy to go from one assay to the next, without sacrificing consistency or performance.

Software
Software width=

Software

Reimagined software makes getting results quick and easy. Simple drag-and-drop functionality for method and sequence creation complements innovative data analysis, to accelerate characterization from start to finish.

Compatability

Convenient 96-well plate format compatible with standard liquid handling systems.

Robustness

Designed for robustness, hardware and software advances ensure repeatability and increased reliability.

Flexibility

Flexible to your workflow requirement, switching between UV and UV-LIF detection is simple and seamless. Integrated detection modules make it easy to go from one assay to the next, without sacrificing consistency or performance.

Software

Reimagined software makes getting results quick and easy. Simple drag-and-drop functionality for method and sequence creation complements innovative data analysis, to accelerate characterization from start to finish.

Take charge of your development timelines.

Zeno DDA EAD/ CID

Adapt to your ever changing drug pipeline

Easily handle new and more complex molecules and their new analytical challenges.

SWATH Acquisition

Reduce method development time

8 channels combined with validated kits and simplified software shorten the time from start up to answer.

Zeno MRMHR

Sensitive impurity quantification you can trust

With high sensitivity UV and Laser Induced Fluorescence detectors the BioPhase 8800 generates results you can trust.

Confident answers at warp speed.

Increase speed to market by making confident decisions quickly, based on sensitive, high-resolution data that you’ve come to trust from SCIEX. This speed of analysis helps retain sample integrity between the first sample and the last – delivering consistent, accurate characterization and quantification for large samples sets, FAST.

CE-SDS

The BioPhase 8800 system provides automated, quantitative and repeatable capillary electrophoresis sodium dodecyl sulfate (CE-SDS) separations, delivering high resolution purity analysis to help you keep pace with workloads while also minimizing sample prep and processing time.

CIEF Analysis

The BioPhase 8800 system delivers rapid and reproducible charge heterogeneity analysis via multi-capillary isoelectric focusing. Parallel processing of 8 samples simultaneously allows for significant improvements in method development and optimization time.

Confident answers at warp speed.

Increase speed to market by making confident decisions quickly, based on sensitive, high-resolution data that you’ve come to trust from SCIEX. This speed of analysis helps retain sample integrity between the first sample and the last – delivering consistent, accurate characterization and quantification for large samples sets, FAST.

analysis-kit

Streamline your workflow.

Validated assay kits simplify operation and minimize user error in core industry applications

Factory-built, multi-capillary, temperature-controlled cartridges help to ensure maximum data reproducibility.

Resource Library

Filter by:
  • Pharma Pharma Protein Purity
  • Technical Notes Technical Notes Technical Notes
  • New

High-throughput multi-capillary SDS gel electrophoresis of proteins

The SCIEX BioPhase 8800 system utilizes a multicapillary format to provide high-throughput sodium dodecyl sulfate gel electrophoresis (SDS-CGE) of proteins, enabling characterization to be performed on multiple samples in parallel and shortening development time.

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  • Pharma Pharma Protein Purity
  • Technical Notes Technical Notes Technical Notes
  • Featured

Acceleration of method optimization for AAV capsid purity analysis using multi-capillary electrophoresis platform

The ability to perform eight separations in parallel on the BioPhase 8800 system allows for faster processing of samples and overall increased throughput to accelerate method development for adeno-associated viruses (AAVs).

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  • Pharma Pharma Gene Therapy
  • Technical Notes Technical Notes Technical Notes
  • New

Genome integrity analysis of adeno-associated viruses (AAV) using multi-capillary gel electrophoresis

The multi-capillary BioPhase 8800 system can run multiple AAV samples with different serotypes or genome sizes simultaneously to accelerate the execution of sensitive AAV genome integrity analysis while retaining excellent resolution, sensitivity and repeatability.

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  • Pharma Pharma Gene Therapy
  • Technical Notes Technical Notes Technical Notes
  • Most Read

BioPhase 8800 System 21 CFR Part 11 Compliance

The BioPhase 8800 system software has the design and features to meet the 21CFR11 compliance and regulatory requirements for operation.

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  • Pharma Pharma Charge Heterogeneity
  • Technical Notes Technical Notes Technical Notes
  • Featured

Rapid and reproducible parallel processing of charge heterogeneity analysis of protein therapeutics by multi-capillary isoelectric focusing

The SCIEX BioPhase 8800 system offers a solution to the limited throughput that current single capillary CIEF systems provide. The new multi-capillary system enables parallel isoelectric focusing analysis for up to 8 samples at a time, allowing for rapid charge heterogeneity analysis of protein therapeutics.

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Learning Hub

Learning Hub success programs provide LC-MS and CE training customized to meet your exact needs.

With a selection of training methods and certifications available, you can build a analysis program that is most suited to your lab and users.

Starting with a clear understanding of your desired learning outcomes, we aim to help you improve lab productivity and consistency by designing and delivering a program that is focused on knowledge advancement and retention.

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