Metabolomics

Accelerate metabolomics discoveries from biological insight to translational impact

Metabolomics research provides a powerful window into biological function, disease mechanisms, and therapeutic response. By measuring small molecule changes across biological systems, researchers can uncover critical insights that advance biomarker discovery, precision medicine, and translational research.

SCIEX helps metabolomics researchers navigate biological complexity with confidence. From targeted quantitation to untargeted discovery and high-throughput screening, our integrated mass spectrometry solutions help achieve deeper metabolome coverage, faster answers, and more confident decision-making. 

Advancing metabolomics research

Turning complex metabolic data into meaningful biological understanding

The metabolome is dynamic, diverse, and constantly changing. Understanding these changes can reveal disease progression, therapeutic response, environmental influences, and opportunities to discover new biomarkers.

SCIEX technologies help researchers move faster from metabolite detection to biological insight. With high-performance mass spectrometry, advanced workflows, and powerful data analysis tools,  our solutions help accelerate discovery with confidence in every result. 

Targeted metabolomics

Quantify known metabolites with confidence

Targeted metabolomics enables researchers to focus on specific metabolites and pathways that drive biological processes and disease states. SCIEX solutions provide the sensitivity, specificity, and reproducibility needed to confidently quantify metabolites across complex biological samples. Whether supporting biomarker validation, clinical research, or pathway analysis, our technologies help researchers generate reliable data and actionable insights.

With SCIEX targeted metabolomics workflows, you can:

  • Quantify metabolites with exceptional sensitivity and specificity
  • Achieve robust, reproducible results across large studies
  • Reveal biological pathways with greater confidence
  • Characterize metabolites through advanced structural elucidation capabilities
  • Generate high-quality data to support translational research and biomarker development

Featured application

Bile acid analysis

Explore advanced approaches for the quantitative analysis and structural characterization of bile acids using SCIEX mass spectrometry solutions.

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Discovery and translational metabolomics

Expand metabolite coverage and uncover new biological insights

Untargeted metabolomics helps researchers discover previously unknown metabolites, identify emerging biomarkers, and gain a more comprehensive understanding of biological systems. SCIEX solutions combine advanced acquisition technologies, including SWATH DIA, ZT Scan DIA, and electron-activated dissociation (EAD), with scalable workflows that help transform large datasets into meaningful biological answers.

With SCIEX discovery metabolomics solutions, you can:

  • Expand metabolite coverage with highly sensitive analyses
  • Accelerate identification and quantitation across complex samples
  • Generate reproducible, high-quality datasets at scale
  • Compare biological conditions with greater statistical confidence
  • Characterize metabolites with enhanced structural information
  • Advance translational research from discovery through validation

When biological questions become more complex, SCIEX helps researchers move faster from observation to understanding. 

High-throughput metabolite screening

Accelerate large-scale studies without compromising data quality

As metabolomics studies continue to grow in scale, researchers need workflows that deliver both speed and confidence. The Echo® MS+ system helps remove bottlenecks across metabolomics workflows, enabling rapid analysis and same-day results for large sample cohorts. Combined with end-to-end workflow solutions, researchers can increase throughput while maintaining high-quality analytical performance.

Benefits include:

  • High-throughput metabolite screening
  • Rapid quantitative analysis
  • Minimal sample consumption
  • Automated workflow integration
  • Faster progression from data generation to decision-making

Technologies supporting metabolomics workflows - Designed to help you uncover deeper biological insights

Metabolomics research depends on trusted data, analytical flexibility, and technologies that can adapt to evolving scientific questions. SCIEX instruments and software are engineered to help researchers generate confident answers across targeted, untargeted, and high-throughput metabolomics applications.

ZenoTOF 8600 system

Drive deeper metabolome coverage with exceptional sensitivity and confident quantitation.

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SCIEX 7600+ system

Combine speed, specificity, and quantitative certainty for demanding metabolomics workflows.

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ZenoTOF 7600 system

Support discovery-driven research with high-resolution mass spectrometry and advanced fragmentation capabilities.

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SCIEX 7500+ system

Achieve reliable performance and exceptional sensitivity for quantitative metabolomics applications.

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Targeted metabolomics with the QTRAP 6500+ system

Enable highly sensitive targeted metabolomics workflows with integrated quantitative and qualitative analysis.

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ExionLC AE system

Discover reproducibility, reliability and carryover performance to match your quantitative workflows. Experience dependability you can count on from injection to injection and batch after batch.

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High-throughput mass spectrometry with the Echo® MS+ system

Accelerate large-scale screening with ultra-high-throughput mass spectrometry.

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SCIEX OS software

Streamline data acquisition, processing, and analysis across metabolomics workflows.

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Service

Keep your instruments performing at their peak with multiple options for response time, repair coverage and maintenance.

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Thought leaders

Extraordinary science in matabolomics - Researchers advancing the future of human health

Discover how leading scientists are using metabolomics to answer complex biological questions, advance disease research, and accelerate the development of precision medicine approaches. Explore stories, applications, and innovations that demonstrate how deeper biological understanding can drive meaningful impact on human health.

Explore extraordinary science
Meet Thomas Hankemeier

Professor of Analytical BioSciences, Leiden Academic Centre for Drug Research (LACDR)

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Stay up to date with the latest trends, scientific breakthroughs, and community insights in proteomics, metabolomics, lipidomics, and biomedical research.

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