The Lipidyzer™ Platform: Transforming the Way You Conduct Lipid Analysis
The Lipidyzer enables life science and lipidomics researchers to accurately quantify over 1100 lipids in a simple and routine manner. The simplicity of the solution allows researchers working in precision medicine to accelerate their biological research and gain insight into the role of lipids in medical conditions such as diabetes, cancer and inflammatory disease.
Quantitation of lipids in complex biological samples is a huge challenge for biological researchers as methodologies can be complex and often require a detailed knowledge of lipid analysis methods. The inherent complexity of the lipidome means that separating different lipid classes and isobaric species in a single analysis method is difficult requiring a high degree of expertise and development time. Even for lipidomics researchers, the challenge of quantifying lipids reproducibly with the demanded degree of accuracy and precision means that biological interpretation of the data is difficult or often impossible. Ultimately a lack of simplified methods and poor quality quantitative data would mean that biological insights into the role of lipid metabolism in disease research are not possible. Without these measurements, life science researchers may be missing potential biomarkers or critical biological observations that could advance their understanding of particular diseases.
The SCIEX Lipidyzer is a fully integrated solution for routine quantitation of over 1100 lipid species, spanning 13 lipid classes. With Lipidyzer researchers are able to generate highly reproducible, accurate and precise quantitation data allowing for statistically relevant biological observations to be drawn from large datasets. Fully streamlined methods, software and internal standard strategies ensure that the highest data quality can be obtained without the need for complex method development. The elimination of uncertainty in data generation can rapidly accelerate your research by letting you focus on the biological implications of the data.
Benefits of the platform:
Specificity - Differential Mobility Spectrometry (DMS) allows you to overcome the challenges of isobaric lipid species overlap to unambiguously identify lipid molecular species
Hear Dr. Joerg Dojahn talk about the challenges in lipid analysis especially for quantitation and how The Lipidyzer Platform overcomes these challenges.
Lipids play an essential role in human physiology, and are significant in researching diseases such as cancer, cardiovascular disease, neurological disorders, and diabetes. Despite their significance, lipid analysis remains frustratingly out of reach for many researchers. Identification and quantification of lipid molecules can be extremely complex, and fragmented testing models complicate things even further. With the Lipidyzer Lipidyzer Platform for Next Generation of Lipidomics, there is now a better, faster, and easier way to differentiate and quantitate over a thousand lipid molecular species.
High Throughput Lipid Analysis Workflow
The robustness of the QTRAP® 5500 system combined with the automated flow injection sample introduction has been proven to deliver reproducible lipid quantitation for high-throughput analyses
The Lipidyzer Platform leverages SCIEX differential mobility separation technology, so you can now distinguish between these isobaric lipid species for confidence in identification and quantitation
The SCIEX novel lipid internal standard kits ensure accurate and reliable quantitation of the samples or pathways you are studying leading to correct conclusions
Detect Relevant Lipids at once for Biological Insight
You need comprehensive quantitative data for a large breadth of lipids in every sample. The Lipidyzer Platform is designed to detect and quantitate more than 1100 lipid species in a single analysis
The Lipidizer Platform is the first end-to-end integrated solution for lipidomics analysis. You go from sample to biological outcome with no method development and no data manipulation – a simple workflow powered by the Lipidomics Workflow Manager that seamlessly takes you from sample in and answers out.
Learn more about the Lipidomics Workflow Manager on the Lipidyzer Platform
Watch these short how-to videos showing how simple the workflow is, from registering kits to collecting results
1103 Lipids from 13 Lipid Species covering LPC, LPE, PC, PE, SM, CE, CER, DCER, HCER, LCER, DAG, TAG and FFA classes.
Lipidyzer will bring us one step forward towards precision medicine as it is a validated, standardized platform, equipped with a fully integrated software solution. Dr Martin Giera, LUMC, Leiden, Netherlands
The Lipidyzer Platform utilizes QTRAP and SelexION Technology, for premium lipid selectivity and quantitative performance. The powerful combination of these technologies with the Lipidomcs Workflow Manager Software and the novel Lipidyzer chemical standard kits delivers accuracy in identification and quantification, never seen before from a single platform. Explore here to learn more about the technology behind the Lipidyzer.
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