Metabolite identification

Advance your drug discoveries with reliable metabolite data that save time and money. Our range of solutions supports routine monitoring and complex identification.

Overview

Confidently complete your metabolite identification studies through your development process with dependable instruments run on intuitive, compliant-ready software.

Our LC-MS systems offer fit-for-purpose sensitive and robust performance.

Small molecule metabolites

Workflow

Imagine the advantage of unambiguous metabolite identification using liquid chromatography-mass spectrometry (LC-MS) reducing the need for additional safety testing during drug discovery. Quickly and easily generate the information you need using routine assays that are robust and efficient, enabling confident decision-making while also saving time and money.

  • More confident identification of the site of metabolism
  • Fit-for-purpose systems
  • Save time and money during drug discovery

Small molecule metabolites

Suited for:

  • More established routine Met ID assays
  • Robust sensitive analysis
ExionLC AE system

Reproducibility, reliability and carryover performance to match your quantitative workflows. Dependability you can count on, from injection to injection and batch after batch.

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X500R QTOF system

A uniquely engineered and versatile QTOF build to handle the demands of any high throughput laboratory.

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Molecule Profiler software

Determine impurities and biotransformations for a wide variety of modalities.

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Service

Keep your instruments performing at their peak, with multiple options for response time, repair coverage and maintenance.

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Small molecule metabolites

Suited for:

  • More challenging Met ID assays requiring additional analytical power
ExionLC AE system

Reproducibility, reliability and carryover performance to match your quantitative workflows. Dependability you can count on, from injection to injection and batch after batch.

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ZenoTOF 7600 system

A high-resolution mass spectrometry solution that combines powerful MS/MS sensitivity, fragmentation technology and a step-change in data independent acquisition.

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Molecule Profiler software

Determine impurities and biotransformations for a wide variety of modalities.

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Service

Keep your instruments performing at their peak, with multiple options for response time, repair coverage and maintenance.

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Oligonucleotide Met ID/biotransformation

Workflow

Complete metabolite assignments from biotransformation of siRNA, antisense and other oligonucleotides using reliable and trustworthy high-resolution mass spectrometry solutions that ensure fragmentation optimization. Identify oligonucleotide-derived metabolites with confidence, despite large isobaric overlaps and high structural similarities. Use custom software modifications that meet your specific analytical needs.

  • Confidently identify and assign metabolites with high-resolution mass spectrometry data
  • Distinguish structurally similar oligonucleotide metabolites with fragmentation optimization
  • Meet your specific analysis needs using custom software modifications

Oligonucleotide Met ID/biotransformation

Suited for:

  • Detection and identification of relevant oligonucleotide biotransformations
ExionLC AE system

Reproducibility, reliability and carryover performance to match your quantitative workflows. Dependability you can count on, from injection to injection and batch after batch.

Learn more
ZenoTOF 7600 system

A high-resolution mass spectrometry solution that combines powerful MS/MS sensitivity, fragmentation technology and a step-change in data independent acquisition.

Learn more
Molecule Profiler software

Determine impurities and biotransformations for a wide variety of modalities.

Learn more
Service

Keep your instruments performing at their peak, with multiple options for response time, repair coverage and maintenance.

Learn more

Oligonucleotide Met ID/biotransformation

ExionLC AE system

Reproducibility, reliability and carryover performance to match your quantitative workflows. Dependability you can count on, from injection to injection and batch after batch.

Learn more
X500B QTOF system

A purpose-built QTOF system, designed specifically to accelerate everyday biologics characterization.

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Molecule Profiler software

Determine impurities and biotransformations for a wide variety of modalities.

Learn more
Service

Keep your instruments performing at their peak, with multiple options for response time, repair coverage and maintenance.

Learn more

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Associated applications

ADME-Tox and DMPK

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High-throughput mass spectrometry

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